Dystrophin: Gene, Protein and Cell Biology (French Edition) [Hardcover]

Susan C. Brown (Editor), Jack A. Lucy (Editor), Marlin Bobrow (Foreword)

Book Description

Publication Date: May 13, 1997 | ISBN-10: 0521550335 | ISBN-13: 978-0521550338 | Edition: 1

This book is concerned with advances in research on dystrophin, and how its absence gives rise to muscular dystrophy. It is the first book to address relationships between the molecular structure and function of dystrophin since the structure of the gene for this protein was elucidated in 1988. The volume covers recent advances in knowledge on the structure of both the dystrophin gene and its associated promoters, and on the protein itself. Functional interactions of dystrophin and its related proteins in the environment of the plasma membrane are a central feature of the book. Other aspects considered are the expression of the dystrophin complex in muscle, in the brain, and at the neuromuscular junction. The book concludes with discussions of muscle regeneration, gene therapy of Duchenne muscular dystrophy, and cellular approaches to the therapy of the disease.

Editorial Reviews

Review

"The book is a useful contribution to the field and fully meets the authors' objectives...thoroughly and well referenced...This is a well-written book." Alvin Telser, Doody's Health Sciences Book Review Journal

Book Description

The absence of dystrophin is the underlying cause of Duchenne muscular dystrophy. This is the first book to address the structure, function, and distribution of dystrophin and its associated proteins in muscle and brain, rather than concentratiing primarily on the disease. It covers an exciting and rapidly expanding field that promises to have important and widespread implications for many aspects of cell biology.

Product Details

• Hardcover: 356 pages
• Publisher: Cambridge University Press; 1 edition (May 13, 1997)
• Language: French
• ISBN-10: 0521550335
• ISBN-13: 978-0521550338
• Product Dimensions: 9.8 x 7 x 0.9 inches
• Shipping Weight: 2 pounds
• Amazon Best Sellers Rank: #5,442,844 in Books (See Top 100 in Books)