Endocrinology of Breast Cancer (Contemporary Endocrinology) [Hardcover]

Andrea Manni (Editor)

Book Description

Publication Date: February 15, 1999 | ISBN-10: 0896035913 | ISBN-13: 978-0896035911 | Edition: 1st

A cutting-edge review of how derangements in the hormonal and growth factor mechanisms controlling normal mammary development lead to breast cancer. Drawing on the multidisciplinary expertise of leading authorities, the book highlights the roles of oncogenes and tumor suppressor genes, spelling out the importance of autocrine/paracrine loops (e.g., stromal epithelial interactions) in supporting breast cancer cell proliferation and the progression to hormone independence. The book's many prominent contributors also illuminate significant recent advances in the biochemistry and physiology of hormone receptors and review the state-of -the-art in the endocrine therapy of breast cancer. Endocrinology of Breast Cancer provides a unique integrated overview of the most significant basic and clinical developments concerning the hormonal aspects of breast cancer.

Editorial Reviews

Review

"A variety of topics are covered, including carcinogenesis, tumor progression, therapeutic options, and benign breast disease. The section divisions of the book make it easy to locate topics of interest. Each chapter has an extensive list of references for further study. Parts IV and V are very thorough in reviewing targets for therapy and endocrine therapy. These chapters provide a good basis from which to understand the development of endocrine therapies. The discussion of normal breast physiology and development is beneficial for the less specialized physician and helps to round out the discussion. "-Doody's Health Science Book Review Journal

"...an invaluable resource for both basic scientists and clinicians who need to update their knowledge about breast cancer biology..."-Cell Biology International 2000

"The authors have succeeded in exploring the most important cell physiology and molecular biology issues pertaining to m endocrinology of breast cancer. For example, there are detailed chapters exploring the relationship between both oncogenes and tumor suppressor genes and breast cancer induction and progression. In addition this volume contains detailed, yet concise, chapters pertaining to the prediction of breast cancer, chemoprevention, and the most novel hormonal treatment strategies. The editor and the authors have clearly worked together to create a focused, yet thorough chapters with minimal overlap, and maximum synergy among chapters" -Quarterly Review of Biology

"...will serve as a comprehensive reference for students, physicians in training, practitioners and investigators....I found the book most helpful as an encyclopedia description of the subject matter. ...I give DR. Manni high marks for having pulled it all together. The goal was to furnish a new state-of-the-art, reference text to fill an important gap." -Elsevier Science

"If you are very interested in the endocrinology of breast development and disease, there probably is no other book available that deals with this area as completely and as currently as this one. Thus, it is a significant contribution to the breast literature."-Modern Pathology

From the Back Cover

In Endocrinology of Breast Cancer, Andrea Manni, MD, organizes a cutting-edge review of how derangements in the hormonal and growth factor mechanisms controlling normal mammary development lead to breast cancer. Drawing on the multidisciplinary expertise of leading authorities, the book highlights the roles of oncogenes and tumor suppressor genes, spelling out the importance of autocrine/paracrine loops (e.g., stromal epithelial interactions) in supporting breast cancer cell proliferation and the progression to hormone independence. The book's many prominent contributors also illuminate significant recent advances in the biochemistry and physiology of hormone receptors and review the state-of -the-art in the endocrine therapy of breast cancer.
Providing a unique, integrated overview of the most significant developments involving the hormonal aspects of breast cancer, Endocrinology of Breast Cancer constitutes an invaluable, broad-ranging resource for all basic scientists, clinicians, and fellows-in-training who want to better understand and treat this most common malignancy.

Product Details

• Hardcover: 391 pages
• Publisher: Humana Press; 1st edition (February 15, 1999)
• Language: English
• ISBN-10: 0896035913
• ISBN-13: 978-0896035911
• Product Dimensions: 10.2 x 7.3 x 1 inches
• Shipping Weight: 2.3 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #4,036,944 in Books (See Top 100 in Books)