Epigenetics 1st Edition

15 customer reviews
ISBN-13: 978-0879697242
ISBN-10: 0879697245
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Editorial Reviews

Review

"The historical accounts of the rise of epigenetics as a field of study, combined with the inclusion of cutting-edging epigenetics research in various biological processes and model organisms, provide the reader with a clear sense of what epigenetics research is about, where it came from, where it is now, and where it is headed. It will prove to be the book that everyone with an interest in epigenetics would want to have and read."
--Cell

"As a whole, Epigenetics is an impressive volume. The contributors provide an accurate survey of the field, from where it began, through where it is today, to where it is heading. Their accounts help set the stage for deepening our understanding of epigenetic phenomena and mechanisms. And the volume will undoubtedly prove to be very useful for students and researchers alike."
--Science

"Overall, Epigenetics is a scholarly work, eminently readable and a welcome resource for anyone looking for an introduction to this new and vibrant field."

--BioEssays

"Beautifully illustrated, this book is a rich source of information for a diverse pool of readers, ranging from graduate students making their first steps in a new field of knowledge to more experienced scientists whose research has led them to unfamiliar grounds.

...what makes "Epigenetics" a truly remarkable and, I believe, a long-lasting achievement is the clear and accessible overview of the major concepts and mechanisms that lay in the foundation of contemporary chromatin research. New details of how specific enzymes and proteins shape chromatin structure and composition may emerge, but the general principles that define how chromatin impacts on many cellular processes are likely to hold true."
--Genetical Research

"In addition to the cutting-edge epigenetic research that is highlighted in this book by eminent scientists in the field, the summaries at the beginning of each chapter, and the multiple tables and colourful illustrations used throughout the book will prove useful in guiding the reader through a discussion of complex biological processes. Undoubtedly, some of these illustrations will be widely used by students and teacher of epigenetics. It is evident that the importance of epigenetics has become widely recognized and this book will be an excellent read for beginners as well as experts in this field."
--Nature Cell Biology

"What is epigenetics? Asking that question will likely return a number of answers that are all some variation of 'heredity that is not due to changes in DNA sequence.' In other words, epigenetics is not genetics. That seems a definition as indistinct as U.S. Supreme Court Justice Potter Stewart's statement, 'I know it when I see it,' about obscenity. The recent volume, Epigenetics, provides well-needed clarity by setting down the fundamental concepts and principles of this emerging science...

With the publication of Epigenetics, this fascinating scientific field no longer needs to be defined by what it is not." --The Quarterly Review of Biology

...an impressive volume...will undoubtedly prove to be very useful for students and researchers alike. -Armelle Corpet and Geneviève Almouzni --Science

...eminently readable and a welcome resource for anyone looking for an introduction to this new and vibrant field. -Joel C. Eissenberg --BioEssays

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Product Details

  • Hardcover: 502 pages
  • Publisher: Cold Spring Harbor Laboratory Press; 1 edition (October 31, 2007)
  • Language: English
  • ISBN-10: 0879697245
  • ISBN-13: 978-0879697242
  • Product Dimensions: 11.4 x 8.7 x 1.1 inches
  • Shipping Weight: 3.6 pounds
  • Average Customer Review: 4.7 out of 5 stars  See all reviews (15 customer reviews)
  • Amazon Best Sellers Rank: #1,530,000 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

19 of 19 people found the following review helpful By Midwest Book Review on April 10, 2007
Format: Hardcover
Epigenetics is a scientific textbook written to teach advanced undergraduate and graduate college students about epigenetic mechanisms, which regulate gene expression in many biological processes. Chapters cover histone modifications, chromatin remodeling, DNA methylation, siRNAs and gene silencing, X-chromosome inactivation, epigenetics in microbes, plants, insects and mammals, and much more. An in-depth, scholarly, and informative instructional reference, interspersed with occasional color photographs and diagrams, featuring an extensive list of references and a general summary at the end of each chapter to aid comprehension. An invaluable educational tool for specialized college science courses, as well as for professionals in the field of biology seeking to sharpen their understanding of modern epigenetics.
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14 of 16 people found the following review helpful By George Edick on May 14, 2007
Format: Hardcover
It is becoming clear that epigenetic mechanisms are responsible for a large number of "genetic" events in the organism, both under normal and pathological circumstances. This advanced text (suitable for advanced undergraduates and beginning graduate students) brings together, in a very readable way, the various mechanisms of epigenetic heredity.
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5 of 5 people found the following review helpful By Einstein on December 15, 2009
Format: Hardcover Verified Purchase
An invaluable resource for people going into the field of epigenetics. The first reference textbook in this quickly growing new field of biology, that has been very carefully and accurately written based on the current literature and research
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4 of 4 people found the following review helpful By Armando-Malwani on July 7, 2009
Format: Paperback
This review provides an excellent overview of the dynamic field of epigenetics. The authors list consists of giants in this field. It is a must read for anyone interested in how phenotypic changes could occur without changes in the DNA sequence would find this a very useful overview. Advanced undergraduates or graduate students would find this book extremely useful.
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2 of 2 people found the following review helpful By Marcela on October 26, 2010
Format: Paperback Verified Purchase
This book contains very detailed molecular information about non-DNA-sequence changes the will affect gene expression.
The epigenetics knowledge is growing so fast that it would be necessary a new revised edition soon.
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19 of 29 people found the following review helpful By John Matlock on December 18, 2006
Format: Hardcover
Wikipedia says: 'Epigenetics is the study of epigenetic inheritance, a set of reversible heritable changes in gene function or other cell phenotype that occur without a change in DNA sequence (genotype).'

That's a pretty general definition, and you can get into some pretty good arguments that this or that word should be changed.

The fundamental discoveries that began the field began to be discussed in 1941, but it grew slowly until fairly recent years. By 2004 the science had developed enough that the 69th Cold Spring Harbor Symposium on Quantitative Biology covered the topic. Many of the authors of this book attended that symposium and the seeds for this book were sown.

The book was written by about forty of the preeminent researchers in the field. It consists of 24 chapters covering virtually all known aspects of the subject. It can serve as a reference work for the current state of the art, or could be used as a text for advanced undergraduate or graduate courses on gene regulation.
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Format: Paperback
Good explanations and an exceptional depth into each topic. You will have difficulty finding this information synthesized so succinctly anywhere else.

This book could use more intuitive diagrams of concepts.
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Format: Paperback Verified Purchase
This is a very good book for the person/student who needs a quick understanding of "what" epigenetics is all about. Good read, non-confusing, and straight to the point. Excellent book.
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