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Epistasis and the Evolutionary Process [Hardcover]

by Jason B. Wolf, Edmund D. Brodie III, Michael J. Wade


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Book Description

July 20, 2000 0195128060 978-0195128062 1
Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.

Editorial Reviews

Review


"I learned a great deal from Epistasis and the Evolutionary Process, and I congratulate the editors on an excellent choice of authors. Graduate students and other scientists will find the book a very useful smorgasbord of recent research into theory and facts of epistasis. The volume does not attempt to resolve the 70-year-old controversy about the importance of epistasis and shifting balance. Instead, it shows that epistasis plays a central role in a much wider and more interesting variety of evolutionary problems than seemed possible even ten years ago."--Science


"This book is important because it marks the transition form a view of epistasis fixed on past controversies to a forward-looking approach where we will have a fresh look at the issues before us and embark on an exciting and significant expansion of the purview of evolutionary theory."--Evolution


About the Author

Jason B. Wolf is at Washington University School of Medicine.

Product Details

  • Hardcover: 344 pages
  • Publisher: Oxford University Press, USA; 1 edition (July 20, 2000)
  • Language: English
  • ISBN-10: 0195128060
  • ISBN-13: 978-0195128062
  • Product Dimensions: 1 x 6.5 x 9.5 inches
  • Shipping Weight: 1.4 pounds
  • Amazon Best Sellers Rank: #5,809,458 in Books (See Top 100 in Books)

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