Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.
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Editorial Reviews
Review
"I learned a great deal from Epistasis and the Evolutionary Process, and I congratulate the editors on an excellent choice of authors. Graduate students and other scientists will find the book a very useful smorgasbord of recent research into theory and facts of epistasis. The volume does not attempt to resolve the 70-year-old controversy about the importance of epistasis and shifting balance. Instead, it shows that epistasis plays a central role in a much wider and more interesting variety of evolutionary problems than seemed possible even ten years ago."--Science
"This book is important because it marks the transition form a view of epistasis fixed on past controversies to a forward-looking approach where we will have a fresh look at the issues before us and embark on an exciting and significant expansion of the purview of evolutionary theory."--Evolution
About the Author
Jason B. Wolf is at Washington University School of Medicine.
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The concept of epistasis plays a central role in the debates that have shaped the modern synthesis of evolutionary biology and in subsequent theoretical depictions of the evolutionary process (Provine 1971). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
raw genotypic values, epistatic genotypic values, phenotype landscape, physiological epistasis, epistatic selection, populational epistasis, negative epistasis, statistical epistasis, dominance genotypic value, fertility loci, significant epistasis, genic values, candidate locus approach, positive epistasis, four morphological traits, bottlenecked lines, synergistic epistasis, epistatic variance, simulans clade, intermediate allele frequencies, meiotic drive systems, complex epistasis, equal phenotype, genetic coadaptation, indirect genetic effects Key Phrases - Capitalized Phrases (CAPs): (learn more)
Maynard Smith, Red Queen, North America, National Science Foundation, Genetic Partners, Gulf Coast, Gulf of Mexico, Jason Wolf, Patrick Phillips, Butch Brodie, Finding References Parent-offspring, Grateful Dead, Laurentide Ice Sheet, Modeling Gene Interaction, New Jersey New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The concept of epistasis plays a central role in the debates that have shaped the modern synthesis of evolutionary biology and in subsequent theoretical depictions of the evolutionary process (Provine 1971). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
raw genotypic values, epistatic genotypic values, phenotype landscape, physiological epistasis, epistatic selection, populational epistasis, negative epistasis, statistical epistasis, dominance genotypic value, fertility loci, significant epistasis, genic values, candidate locus approach, positive epistasis, four morphological traits, bottlenecked lines, synergistic epistasis, epistatic variance, simulans clade, intermediate allele frequencies, meiotic drive systems, complex epistasis, equal phenotype, genetic coadaptation, indirect genetic effects Key Phrases - Capitalized Phrases (CAPs): (learn more)
Maynard Smith, Red Queen, North America, National Science Foundation, Genetic Partners, Gulf Coast, Gulf of Mexico, Jason Wolf, Patrick Phillips, Butch Brodie, Finding References Parent-offspring, Grateful Dead, Laurentide Ice Sheet, Modeling Gene Interaction, New Jersey New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 8
books:
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12
books
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- The Origin Of Species: 150th Anniversary Edition by Charles Darwin on page 197
- Biological Science: Volume 1 by Roland Soper in Back Matter
- New York by Tama Janowitz in Back Matter
- Population Genetics by F. B. Christiansen on page 118
- On the Origin of Species (Penguin Classics) by Charles Darwin on page 197
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- Phenotypic Plasticity: Functional and Conceptual Approaches (Life Sciences) by Thomas J. DeWitt on 4 pages
- Population Genetics and Microevolutionary Theory by Alan R. Templeton in Back Matter (1), Back Matter (2), and Back Matter (3)
- Genetics of Adaptation (Georgia Genetics Review) by Rodney Mauricio on page 47, page 104, and page 105
- Niche Construction: The Neglected Process in Evolution (MPB-37) (Monographs in Population Biology) by F. John Odling-Smee in Back Matter (1), and Back Matter (2)
- Current Topics in Developmental Biology, Volume 66 by Gerald P. Schatten on page 212, and page 213
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