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Erythropoietin and the Nervous System
 
 
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Erythropoietin and the Nervous System [Hardcover]

Ahmet Höke (Editor)

Price: $148.00 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

0387300104 978-0387300108 November 29, 2005 1

Erythropoietin (EPO) is a chemokine hormone that is widely distributed throughout the body. In addition to its traditional role as a hormone that stimulates red blood cell production, in recent years many laboratories have shown that EPO can act as a neuroprotective compound in a variety of injury paradigms in the nervous system. Past experience with relatively safety profile of this FDA-approved drug makes it an ideal candidate to take it into clinical trials for neuroprotection. We are on the verge of major clinical trials using this drug for neuroprotection in diseases ranging from stroke, to transverse myelitis to chemotherapy-induced peripheral neuropathy. This is the first book of its kind that brings together researchers from many different disciplines of neuroscience to review the current state-of-the-art in EPO and the nervous system. This book will benefit scientists and clinicians interested in neuroprotection in the broadest sense.


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Editorial Reviews

From the Back Cover

Erythropoietin and the Nervous System is the first book of its kind to bring together researchers from many different disciplines of neuroscience to present a current state-of-the-art review of multiple aspects of erythropoietin research as it relates to the nervous system. Erythropoietin (EPO) is a chemokine hormone that is widely distributed throughout the body. In addition to its traditional role as a hormone that stimulates red blood cell production, in recent years many laboratories have shown that EPO can act as a neuroprotective compound in a variety of injury paradigms in the nervous system. Past experience with the relatively safety profile of this FDA-approved drug makes it an ideal candidate to take into clinical trials for neuroprotection. We are on the verge of major clinical trials using this drug for neuroprotection in diseases ranging from stroke, to transverse myelitis to chemotherapy-induced peripheral neuropathy.

This book should stimulate new research on erythropoietin and the nervous system and bring new investigators to the field. It will benefit scientists and clinicians interested in neuroprotection in the broadest sense.


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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
exocytotic glutamate release, vivo evidence that erythropoietin, chronic neuroprotection, experimental spinal cord ischemic injury, epo expression, focal permanent cerebral ischemia, neurotrophic sequence, developing human central nervous system, epo gene expression, neurons from ischemic damage, acute neuroprotection, neuronal apoptosis after cerebral ischemia, chemical ischemia, prevents axonal degeneration, rat retinal ganglion cells, erythropoietin gene expression, erythropoietic effect, stroke tolerance, following ischemic stroke, motor neuron apoptosis, erythropoietin protects, experimental spinal cord trauma, root crush, erythropoietin receptor, experimental brain injury
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Proc Natl Acad Sci, Biol Chem, Brain Res, Pediatr Res, Neurosci Res, Cereb Blood Flow Metab, Exp Med, Biochem Biophys Res Commun, Kidney Int, Neuropathol Exp Neurol, Neurosci Lett, Ann Neurol, Biol Neonate, Mol Cell Biol, Nat Med, Acta Neuropathol, Clin Invest, Invest Ophthalmol Vis Sci, Mol Med, Nephrol Dial Transplant, Neurobiol Dis, Trends Neurosci, Biol Psychiatry, Dev Neurosci, Neurol Sci
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