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Essential Concepts in Molecular Pathology [Hardcover]

William B. Coleman (Editor), Gregory J. Tsongalis (Editor)

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Book Description

February 23, 2010 0123744180 978-0123744180 1

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school.

  • Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease
  • Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease
  • In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology.
  • "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases.
  • Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine
  • Student web site hosts "self-assessment" questions; Professor web site hosts all figures from book
  • Each chapter ends with Key Summary Points and Suggested Readings

 


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    Editorial Reviews

    From the Back Cover

    "Essential Concepts in Molecular Pathology provides the reader with what is missing from most targeted introductions to pathology; the cell biology behind pathophysiology. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ; the text provides the student with the background necessary for the understanding of today's advances in pathology and medicine. The book is compact, easy to follow, filled with useful tables and figures and deserves reading by students and professionals interested in the molecular basis of disease."

    --Howard Reisner PhD, Professor of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, North Carolina, USA

    "Finally, a book that captures the real world environment of molecular diagnosis and pathology of a comprehensive range of diseases while establishing a foundation in the basics of molecular biology is available in Essential Concepts in Molecular Pathology! The clinical hospital laboratory has become a critical link in the rapidly changing way in which we diagnose disease with respect to molecular diagnostics. It has been challenging to embed the fundamentals of molecular diagnosis to students of clinical laboratory science (CLS) programs without a resource of the most current, state-of-the-art molecular foundations. Essential Concepts has not only offered an outstanding textbook to build future CLS practitioners, but it also represents an outstanding "working" resource for the established molecular pathologist and others involved biomedical research.  As the title states, the individual chapters relate the most important points about specific topics with excellent figures and examples while directing the user to Suggested Readings for more in-depth coverage. The editors have put together a wonderful resource for allied health programs and similar professionals to use as a textbook or as a companion to a more comprehensive molecular pathology offering."

    --Rodney E. Rohde, MS, SV, SM, MP (ASCP), Associate Professor, Texas State University-San Marcos, Clinical Laboratory Science, San Marcos, TX, USA

    About the Author

    Dr. William B. Coleman is Professor of Pathology and Laboratory Medicine and Director of Graduate Studies for the Molecular and Cellular Pathology Graduate Program at the University of North Carolina School of Medicine (Chapel Hill, NC). Dr. Coleman is co-director of the UNC Program in Translational Medicine, and co-director of the Environmental Pathology Predoctoral and Postdoctoral Training Program. In addition, he is affiliated with the Curriculum in Toxicology and is a member of the UNC Lineberger Comprehensive Cancer Center. Dr. Coleman is actively involved in teaching biomedical graduate students and is a three-time recipient of the Joe W. Grisham Award for Excellence in Graduate Student Teaching from the Molecular and Cellular Pathology graduate students at UNC-Chapel Hill. Dr. Coleman is active in the leadership of the American Society for Investigative Pathology, and is a member of the American Association for Cancer Research. He serves on the editorial boards of Clinica Chimica Acta, The American Journal of Pathology, Experimental and Molecular Pathology, Archives of Pathology and Laboratory Medicine, and Laboratory Investigation, and has served as an ad hoc reviewer for 48 other journals. Dr. Coleman's major research interests are in the molecular pathogenesis of human cancers, with a specific interest in breast cancer epigenetics, liver carcinogenesis, and lung cancer biology. His research has been funded by the NIH/NCI, The Susan G. Komen Breast Cancer Foundation, Friends for an Earlier Breast Cancer Test, and the UNC Lineberger Comprehensive Cancer Center. Dr. Coleman is the author of over 100 original research articles, reviews, and book chapters. In addition, Dr. Coleman has co-edited or co-authored six books on topics related to molecular pathology, molecular diagnostics, and the molecular pathogenesis of human cancer.


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