The book reviews the latest data on all of the different biochemical steps that comprise base excision repair (BER), the primary pathway for removal of alkylation, hydrolytic and oxidative damage to DNA. This monograph covers various aspects from excision of damaged or mismatched bases and repair of baseless sites, through a discussion of the DNA polymerases needed for BER, and eventually to the enzymes that complete the BER process. Where appropriate, the cytotoxic and mutagenic consequences of a failure to complete any particular step in the process are outlined.
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Inside This Book
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First Sentence:
An essential requirement for all organisms is to maintain genomic integrity. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
alkylation exposure, fpg gene, glycosylase gene, base excision repair, oxidized purines, alkylation damage, glycosylase activity, clease activity, base flipping, exonuclease domain, glycosylic bond, minal domain, nicking activity, cytosine deamination, repair polymerase, lian cells, mutational specificity, dent pathway, monofunctional alkylating agents, excision mechanism, hydrolytic deamination, repair reaction, nucleotide gap, abasic site, excision repair pathway Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, Proc Natl Acad Sci, Nucleic Acids Res, Mol Cell Biol, Mutat Res, Mol Biol, Nucl Acids Res, Biochem Biophys Res Commun, Annu Rev Biochem, Landes Bioscience, New York, Mol Gen Genet, Mutation Res, Cancer Res, Biochim Biophys Acta, Drosophila Rrpl, Plenum Press, The Netherlands, Academic Press, Current Biol, Mol Cellul Biochem, Molec Gen Genet, Mot Gen Genet, Swiss Prot New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
An essential requirement for all organisms is to maintain genomic integrity. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
alkylation exposure, fpg gene, glycosylase gene, base excision repair, oxidized purines, alkylation damage, glycosylase activity, clease activity, base flipping, exonuclease domain, glycosylic bond, minal domain, nicking activity, cytosine deamination, repair polymerase, lian cells, mutational specificity, dent pathway, monofunctional alkylating agents, excision mechanism, hydrolytic deamination, repair reaction, nucleotide gap, abasic site, excision repair pathway Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, Proc Natl Acad Sci, Nucleic Acids Res, Mol Cell Biol, Mutat Res, Mol Biol, Nucl Acids Res, Biochem Biophys Res Commun, Annu Rev Biochem, Landes Bioscience, New York, Mol Gen Genet, Mutation Res, Cancer Res, Biochim Biophys Acta, Drosophila Rrpl, Plenum Press, The Netherlands, Academic Press, Current Biol, Mol Cellul Biochem, Molec Gen Genet, Mot Gen Genet, Swiss Prot New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 5
books:
- Chromosome Damage and Repair (NATO Advanced Study Institutes Series) by Erling Seeberg on page 4, and page 21
- Nucleic Acids (Methods in Molecular Biology) by John M. Walker on page 75, and page 99
- Base Excision Repair, Volume 68 (Progress in Molecular Biology & Translational Science) by Sankar Mitra on page 166
- Molecular Biology of Mutagens and Carcinogens by Beatrice Singer on page 21
- Growth Control During Cell Aging by Eugenia Wang on page 115
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