This volume includes 59 key papers on differential display and related technologies selected from the pages of BioTechniques journal by two pioneers of this important expression methodology -- Dr. Arthur Pardee, the creator of differential display, and Dr. Michael McClelland who developed the closely related AP-PCR technique. A special feature of this book is the original review chapter prepared by Drs. Pardee and McClelland, commenting on the state of differential display today. To provide the most current information possible, many articles include "Updates" prepared by their original authors. This volume encompasses many important modifications made to the differential display in recent years and will provide the reader with a good overview of the technique and a broad array of useful protocols.
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