Fluorine-containing Amino Acids: Synthesis and Properties [Hardcover]

Valery P. Kukhar (Editor), V. A. Soloshonok (Editor)

Book Description

Publication Date: March 28, 1995 | ISBN-10: 0471952036 | ISBN-13: 978-0471952039 | Edition: 1

In recent years, organo-fluorine chemistry has made a marked impact on the design and synthesis of a large variety of biologically active molecules, such as steroids, carbohydrates, amines, amino acids, peptides and other natural products. Naturally occurring amino acids play a pivotal role in living systems, and therefore synthetic fluorine-containing amino acids have been of significant interest to researchers working towards the understanding and modification of physiological processes. Fluorine-containing Amino Acids:
* is the first volume devoted to the synthesis and properties of fluorine-containing amino acids
* pays special attention to the preparation of enantiomerically pure acids (which are essential to the modern pharmaceutical industry)
* deals with a rapidly expanding field of research
* has been written by experienced researchers who are responsible for many developments in the field
* highlights the interdisciplinary nature of this topic
Fluorine-containing Amino Acids is the only dedicated reference in this subject and will be essential for researchers in synthetic organic, peptide, natural product, and medicinal chemistry and biochemistry.

Editorial Reviews

From the Publisher

More than 700 amino acids (AAs) have been found in nature and their number is continually increasing. Internationally renowned scientists critically examine the chemistry of fluorine-containing amino acids (FAAs) and the existing knowledge regarding their biological properties. A synthesis of FAAs by methods of acid, organofluorine and organometallic chemistry; enzymatic and chromatographic resolution of racemic FAAs; biological characteristics of FAAs and their applications are among the subjects covered.

From the Back Cover

In recent years, organo-fluorine chemistry has made a marked impact on the design and synthesis of a large variety of biologically active molecules, such as steroids, carbohydrates, amines, amino acids, peptides and other natural products. Naturally occurring amino acids play a pivotal role in living systems, and therefore synthetic fluorine-containing amino acids have been of significant interest to researchers working towards the understanding and modification of physiological processes. Fluorine-containing Amino Acids:

• is the first volume devoted to the synthesis and properties of fluorine-containing amino acids
• pays special attention to the preparation of enantiomerically pure acids (which are essential to the modern pharmaceutical industry)
• deals with a rapidly expanding field of research
• has been written by experienced researchers who are responsible for many developments in the field
• highlights the interdisciplinary nature of this topic

Fluorine-containing Amino Acids is the only dedicated reference in this subject and will be essential for researchers in synthetic organic, peptide, natural product, and medicinal chemistry and biochemistry.

Product Details

• Hardcover: 422 pages
• Publisher: Wiley; 1 edition (March 28, 1995)
• Language: English
• ISBN-10: 0471952036
• ISBN-13: 978-0471952039
• Product Dimensions: 9 x 6 x 1.1 inches
• Shipping Weight: 1.7 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #5,119,338 in Books (See Top 100 in Books)