The Fly Neuromuscular Junction: Structure and Function, Volume 75: Second Edition (International Review of Neurobiology.) [Hardcover]

Vivian Budnik (Editor), Catalina Ruiz-Canada (Editor)

Book Description

Publication Date: October 31, 2006 | ISBN-10: 0123736137 | ISBN-13: 978-0123736130 | Edition: 1

The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful tool to understand the normal function of these genes.
This book reviews outstanding work by recognized leaders in the fields of Drosophila cellular neurogenetics including developmental neurobiology, mechanisms of synaptic function, and experience dependent changes at synapses. The book also includes step-by-step protocols to study the cellular biology of the NMJ, making it a vital resource for researchers beginning their investigations with this system, for those who are training students and postdoctoral fellows in this area, or simply as a general reference material for neuroscientists and neuroscience professors in general.

* Provides a synthesis of the main topics in modern neurogenetics
* Includes step-by-step protocols for the use of the Drosophila NMJ system in neurobiology lab research
* Offers genetic approaches to study synapse development and function
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Editorial Reviews

Book Description

Reference for studying the Drosophila as a model system for neuroscience research.

Product Details

• Hardcover: 424 pages
• Publisher: Academic Press; 1 edition (October 31, 2006)
• Language: English
• ISBN-10: 0123736137
• ISBN-13: 978-0123736130
• Product Dimensions: 9.1 x 6 x 1 inches
• Shipping Weight: 1.8 pounds
• Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #3,387,538 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

5.0 out of 5 stars Excellent tool for developmental neurobiologists, October 3, 2011

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Leafice - See all my reviews

This review is from: The Fly Neuromuscular Junction: Structure and Function, Volume 75: Second Edition (International Review of Neurobiology.) (Hardcover)

This book is an indispensible tool for developmental neurobiologists, especially those who use or are interested in Drosophila. It not only includes thorough reviews of each area of fly NMJ research but also covers detailed protocols of several key techniques. Each chapter is written by experts and leaders in the specific fields. It is still a rather comprehensive guide to the field of fly NMJ even after several years of its publication.