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The first half of the book sets up the opposition in literary terms. Untrammeled exploration is the taking of what cultural institutions say must not be taken; Shattuck traces this exploration from the myth of the fire stealer Prometheus, through Eve's eating of the interdicted apple in the Bible and Paradise Lost, Ulysses' illicit voyage (Book XXVI, Dante's Inferno), and many other literary representations. The opposing way of approaching prohibitions is found in two instances (both written by women, a point Shattuck could make more of) of liberation that comes through self-limitation: La Princesse de Cleves and the poetry of Emily Dickinson. The second half of Forbidden Knowledge applies these oppositions to life, as in the social consequences of violent pornography (e. g., De Sade's influence on Ted Bundy) and scientific exploration (the human genome project) that seems to promise complete control over human existence. Shattuck's range of literary reference is divertingly breathtaking: Socrates and rap, Aeschylus and Woody Allen, Goethe, Ghandi, Melville, Maimonides, Walter Pater, Democritus, Roland Barthes, Perrault--aw, hell, everything: if you've taken Western Literature at any quarter-baked college or university, you'll come upon something you've read. And Shattuck will illuminate it from the alternative perspectives of pleonexia vs. portee.
It would have been simple-minded, easy, and instantly suspect to compose a polemic for intellectual freedom. This Shattuck does not do. He argues instead that philosophical and scientific thought--the law of infinite regress, for instance--affirms the impossibility of complete knowledge. Although human nature is such that exploration cannot be stopped, the ways in which knowledge is applied can be controlled. Incompleteness is inevitable--and humanizing. "Be lowly wise" (Paradise Lost, Book VIII).
I summarize shamelessly because I am confident that anyone who reads this will want the book. It is learned, original, many-sided, allusive without crowing, invigorating, earnest yet sophisticated, written with humor and grace. In our age, when science and art have displaced religion, only scientific and aesthetic arguments can hold weight. Forbidden Knowledge is the largest and most valuable contemporary book I have read to address in large, relevant compass the question of moral responsibility. And it is the only one to do so convincingly.