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Forensic DNA Typing: Biology and Technology Behind STR Markers
 
 

Forensic DNA Typing: Biology and Technology Behind STR Markers [Hardcover]

John M. Butler (Author)
4.8 out of 5 stars  See all reviews (19 customer reviews)


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There is a newer edition of this item:
Forensic DNA Typing, Second Edition: Biology, Technology, and Genetics of STR Markers Forensic DNA Typing, Second Edition: Biology, Technology, and Genetics of STR Markers 4.8 out of 5 stars (19)
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Book Description

February 14, 2001 012147951X 978-0121479510 1st
Forensic DNA Typing focuses on the biology and technology behind short tandem repeat (STR) markers and the most common forensic DNA analysis method used today. This comprehensive handbook will help forensic scientists gain a better understanding of STRs and the procedures needed to properly analyze them, while helping professionals in the law enforcement and legal communities comprehend the complexities of DNA profiling. It will also help laboratories meet the training requirements in the new DNA Advisory Board Quality Assurance Standards.

The first few chapters of Forensic DNA Typing provide a thorough introduction to the topic for readers who might be less familiar with DNA, while providing a useful review for more advanced readers. It goes on to cover new genetic markers and information on rapidly changing technologies to help professionals make accurate identifications through DNA typing. Detailed illustrations and examples are used throughout. The book concludes with reviews of the DNA testing performed in high-profile cases such as the O.J. Simpson trial, the President Clinton-Monica Lewinsky affair, the Tomb of the Unknown Soldier, the Thomas Jefferson-Sally Hemings family controversy, and others.

John Butler has been involved in the validation of the short tandem repeat markers that form the basis of the FBI's nationwide DNA database, CODIS, and in the development of new and innovative technologies. His talent for explaining complex information is apparent in the clear organization, illustrations, and straightforward language of this text. Forensic DNA Typing has already established itself as the standard reference in the field.

Key Benefits:
* Chapters cover the topic from introductory level right up to "cutting edge" research
* Forensic scientists learn about the new methods and technologies required by STR typing
* DNA laboratories find out how to meet the training requirements of the DNA Advisory Board Quality Assurance Standards (listed in Appendix III)
* Lawyers and law enforcement professionals understand the science behind the techniques
* All readers can use the information listed on suppliers of DNA analysis equipment, products and services

* Provides a comprehensive look at the biology, technology, and applications of DNA typing
* Focuses on the major molecular biological technique currently being used throughout the world
* Uses a wide array of illustrations and examples to make the material easy to understand
* Progresses from basic introductory information to cutting-edge research
* Designed for forensic scientists, law enforcement and legal professionals, and students in related fields
* Provides DNA analysts with all the reported alleles for the 13 CODIS STR loci, including sizes and sequences
* Includes the DNA Advisory Board Quality Assurance Standards
* Reviews DNA testing performed in high-profile cases


Editorial Reviews

Review

"...a well written and informative book...The author has succeeded in presenting complex biological and technical information on STR markers in a way that allows the reader to clearly visualize and understand the principles involved...this book would serve as an excellent introductory textbook for students in forensic science or as a reference text for scientists employed in forensic biology or related fields."
- Peter Bilous, RCMP Forensic Laboratory Services, Edmonton, Alberta, Canada, for the CANADIAN SOCIETY OF FORENSIC SCIENCES JOURNAL, December 2001

"Forensic DNA Typing provides a wealth of general and background information on STRs and details on current and future technologies employed in forensic DNA typing...I would strongly recommend this book as a training aid for new analysts or a DNA typing reference for forensic scientists."
- Brendan F. Shea, DNA Analysis Unit, Federal Bureau of Investigation, for FORENSIC SCIENCE COMMUNICATIONS

"As a guide and reference for the non-specialist this book is extremely useful. The practical details and methods make it a valuable purchase for scientists, doctors, lawyers and police officers. It is clear and practical. The chapter of case studies at the end puts informative flesh on the subject which is still mysterious to many in the forensic field. The book goes a long way to demystifying DNA and I would recommend it highly." Winner of the Highly Commended Award for 2001"
- British Medical Association

"...While there are many books that discuss the principles of molecular biology and forensic testing, none have dealt solely with the biology, technology, and applications of DNA typing in such a comprehensive fashion as this one. Dr. Butler has a unique perspective on DNA typing. His background...uniquely [qualifies] him as an expert in the forensic field...a very readable text..."
--Dennis J. Reeder, Ph.D., FBI DNA Advisory Board, from the Foreword

.the book has so many qualities that it is worth considering for everybody who is involved in modern forensic genetic DNA typing or is dependent on the results and the interpretation of the results. - Internet Journal of Forensic Medicine

Book Description

This enormously successful book gains ten new chapters on DNA typing sytems, mitochondrial DNA markers, Y chomosomes, and statistical analysis of short tandem repeat (STR) typing data --providing valuable insight on this fascinating new technology! --This text refers to an out of print or unavailable edition of this title.

Product Details

  • Hardcover: 322 pages
  • Publisher: Academic Press; 1st edition (February 14, 2001)
  • Language: English
  • ISBN-10: 012147951X
  • ISBN-13: 978-0121479510
  • Product Dimensions: 10 x 7.7 x 0.9 inches
  • Shipping Weight: 2.3 pounds
  • Average Customer Review: 4.8 out of 5 stars  See all reviews (19 customer reviews)
  • Amazon Best Sellers Rank: #1,311,816 in Books (See Top 100 in Books)

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Customer Reviews

19 Reviews
5 star:
 (16)
4 star:
 (2)
3 star:
 (1)
2 star:    (0)
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Average Customer Review
4.8 out of 5 stars (19 customer reviews)
 
 
 
 
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Most Helpful Customer Reviews

8 of 8 people found the following review helpful:
5.0 out of 5 stars Clearly, an outstanding piece of work!, March 28, 2001
By 
Diana K Midgley (BURKE, VA United States) - See all my reviews
This review is from: Forensic DNA Typing: Biology and Technology Behind STR Markers (Hardcover)
While Dr. Butler's book on DNA typing is clearly based on experience and profound understanding of the subject, I was most impressed with the readability. I was thrilled to find principles illustrated by examples from current events! Students of science will find this book refreshing. Well written (and edited)!
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9 of 10 people found the following review helpful:
5.0 out of 5 stars The Breakthrough in Forensics This Year! - A Must Have Book!, March 20, 2001
By 
Dr. Robert S. Jones (Los Angeles, CA USA) - See all my reviews
This review is from: Forensic DNA Typing: Biology and Technology Behind STR Markers (Hardcover)
Dr. Butler takes a very complex subject and makes it easy enough for the novice to understand, yet is comprehensive enough for the professional research analyst. It is full of excellent research and observations on one of the most exciting and innovative technologies in DNA research that has been discovered in recent years. This book, without a doubt, will stand the test of time as being the authoritative reference on DNA forensic research. This book is packed with research and information that will enlighten you to the technological breakthroughs that are being made in forensic science. I have heard Dr. Butler speak and read several of his papers. He is without question the expert in DNA analysis with STR markers and this book has the distinction of being the best book ever written on the subject. Get this book, study it and find out why STR markers are the groundbreaking method for DNA analysis. If you are in any way involved with DNA research, you will find this book a desktop reference you will turn to again and again.
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6 of 6 people found the following review helpful:
5.0 out of 5 stars Marvelous work!, March 20, 2001
By 
This review is from: Forensic DNA Typing: Biology and Technology Behind STR Markers (Hardcover)
This book has opened my eyes to the vast world of DNA analysis. It is an invaluable resource to those who want to understand how criminal justice will advance into the new millennium. Butler's text will be the keystone of DNA analysis in the future. I look forward to revised editions as new things arise.
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Inside This Book (learn more)
First Sentence:
"In the darkness of the early morning hours of 26 August 1999, a young University of Virginia student awoke to find a gun pointed at her head." Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
stutter products, forensic casework samples, stutter percentage, microvariant alleles, convicted offender samples, genotyping software, allelic ladders, core loci, allele peak, human identity testing, overlapping alleles, equivalent alleles, allele calls, allele transfers, internal lane standard, allele dropout, paternity testing laboratories, developmental validation, random match probability, internal size standard, fluorescence imaging system, tetranucleotide repeat polymorphism, mixture interpretation, sizing standard, autosampler tray
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Promega Corporation, Journal of Forensic Sciences, United States, International Journal of Legal Medicine, Forensic Science Service, Applied Biosystems, American Journal of Human Genetics, Perkin Elmer Corporation, Sally Hemings, Genetic Analyzer, Eston Hemings, Foster City, Profiler Plus, Analytical Chemistry, Nucleic Acids Research, Advisory Board, Human Genome Project, United Kingdom, Genome Research, Human Molecular Genetics, Nature Genetics, Proceedings of the Eighth International Symposium, Proceedings of the Ninth International Symposium, Thomas Woodson, Amplification Kit User's Manual
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