Forensic DNA Profiling Protocols (Methods in Molecular Biology) [Hardcover]

Patrick J. Lincoln (Editor)

Book Description

Publication Date: June 15, 1998 | Series: Methods in Molecular Biology (Book 98)

Leading forensic experts from around the world describe in detail their time-proven methods for identity testing through DNA analysis. Their state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The book covers PCR- based test systems, the now widely used STR typing systems (complete with details of both manual and automated detection systems), repeat unit mapping (MVR), direct phase minisequencing, capillary electrophoresis, and direct blotting. Also fully discussed are the recovery of DNA from a wide range of sample types (blood, semen, skeletal remains, and saliva), species testing, sex determination, and mitochondrial DNA testing. This state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The methods include the recovery of DNA from a large range of sample types, analysis of DNA as single and multi-locus VNTR probes, PCR amplification of STR and other loci, and mitochondrial sequencing. The expert scientists writing here-many from laboratories around the world-also discuss how to interpret the results in cases of unknown identity and disputed parentage.

Editorial Reviews

Review

"For the first time the major laboratory procedures used in human identification are brought together in one book. . .contains much valuable information."-Journal of the Forensic Science Society

From the Back Cover

In Forensic DNA Profiling Protocols, leading forensic experts from around the world describe in detail their time-proven methods for identity testing through DNA analysis. Their state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The book covers PCR-based test systems, the now widely used STR typing systems (complete with details of both manual and automated detection systems), repeat unit mapping (MVR), direct-phase minisequencing, capillary electrophoresis, and direct blotting. Also fully discussed are the recovery of DNA from a wide range of sample types (blood, semen, skeletal remains, and saliva), species testing, sex determination, and mitochondrial DNA testing. Forensic DNA Profiling Protocols captures and makes practical for all laboratories the whole array of new technologies and techniques that have revolutionized forensic science. The readily reproducible methods elucidated here represent the state-of-the-art for those scientists who want to introduce, establish, and perfect DNA identification techniques in their laboratories.

Product Details

• Hardcover: 309 pages
• Publisher: Springer; 1st edition (June 15, 1998)
• Language: English
• ISBN-10: 0896034437
• ISBN-13: 978-0896034433
• Product Dimensions: 9.3 x 6.3 x 1 inches
• Shipping Weight: 1.5 pounds
• Amazon Best Sellers Rank: #2,725,400 in Books (See Top 100 in Books)