Dog Frontline Plus is the #1 selling Flea & Tick control product! It kills fleas, ticks, and chewing lice within 48 hours of application and contains an insect growth controller that eliminates eggs and larvae. Frontline Plus flea tick control is a fast-acting treatment that can be applied as a preventative year-round. Each application protects your dog for a full month and does not need reapplied for 30 days. Frontline Plus for small dogs or large dogs is available based on your dog's weight. These may sometimes be referred to as Frontline Plus Orange or Frontline Plus Purple, respectively. Use on puppies over 8 weeks of age. Waterproof. Frontline Plus 3 Pack or 6 Pack is available for your convenience.