Fundamental Concepts of Bioinformatics [Paperback]

Dan E. Krane (Author), Michael L. Raymer (Author)

Book Description

Publication Date: September 22, 2002 | ISBN-10: 0805346333 | ISBN-13: 978-0805346336 | Edition: 1

Fundamental Concepts of Bioinformatics is the first book co-authored by a biologist and computer scientist that is specifically designed to make bioinformatics accessible and provide readers for more advanced work. Readers learn what programs are available for analyzing data, how to understand the basic algorithms that underlie these programs, what bioinformatic research is like, and other basic concepts. Information flows easily from one topic to the next, with enough detail to support the major concepts without overwhelming readers. Problems at the end of each chapter use real data to help readers apply what they have learned so they know how to critically evaluate results from both a statistical and biological point of view.

Editorial Reviews

From the Back Cover

Fundamental Concepts of Bioinformatics is the first book co-authored by a biologist and computer scientist that is specifically designed to make bioinformatics accessible and provide readers for more advanced work. Readers learn what programs are available for analyzing data, how to understand the basic algorithms that underlie these programs, what bioinformatic research is like, and other basic concepts. Information flows easily from one topic to the next, with enough detail to support the major concepts without overwhelming readers. Problems at the end of each chapter use real data to help readers apply what they have learned so they know how to critically evaluate results from both a statistical and biological point of view. Focus on fundamentally important algorithms at the core of bioinformatics. For anyone interested in bioinformatics (in biology or computer science), computational biology, molecular biology, or genomics.

Product Details

• Paperback: 320 pages
• Publisher: Benjamin Cummings; 1 edition (September 22, 2002)
• Language: English
• ISBN-10: 0805346333
• ISBN-13: 978-0805346336
• Product Dimensions: 8.2 x 6.6 x 0.6 inches
• Shipping Weight: 1.1 pounds (View shipping rates and policies)
• Average Customer Review: 4.0 out of 5 stars  See all reviews (3 customer reviews)
• Amazon Best Sellers Rank: #719,974 in Books (See Top 100 in Books)
  • #91 in Books > Professional & Technical > Professional Science > Biological Sciences > Bioinformatics

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Customer Reviews

Most Helpful Customer Reviews

18 of 23 people found the following review helpful:

4.0 out of 5 stars good undergrad/opening text, September 22, 2003

By 

K. Kumar "Half my Paycheck goes to Amazon" (Chicago, IL - USA) - See all my reviews
(REAL NAME)   

This review is from: Fundamental Concepts of Bioinformatics (Paperback)

Features

First bioinformatics primer for undergraduates. Personable writing style and numerous analogies make this text accessible to undergraduates.

Focus on fundamentally important algorithms at the core of bioinformatics.

Easy-to-do "paper and pencil" calculations make fundamental algorithms unintimidating for biology students and accessible to students with limited experience in computer programming.

Combined expertise (biology and computer science) of author team ensures an integrated approach and an appreciation for the biology and computer science tools and perspectives.

End-of-Chapter summaries tie together key concepts and provide real-world examples of the algorithms presented.

Detailed solutions to selected text questions are provided in the back of the text so students can check their answers.

Annotated Reading Material sections at the end of each chapter direct students to additional resources for further explanation.

Questions and problems at the end of each chapter help students apply their understanding of the material.

Contents

MOLECULAR BIOLOGY AND BIOLOGICAL CHEMISTRY.
DATA SEARCHES AND PAIRWISE ALIGNMENTS.
SUBSTITUTION PATTERNS.
DISTANCE-BASED METHODS OF PHYLOGENETICS.
CHARACTER-BASED APPROACHES TO PHYLOGENETICS.
GENOMICS AND GENE RECOGNITION.
PROTEIN FOLDING.
PROTEOMICS.

6 of 7 people found the following review helpful:

5.0 out of 5 stars A great textbook and reference book for both students and researchers., September 19, 2006

By 

J. Yang (Cambridge) - See all my reviews
(REAL NAME)   

This review is from: Fundamental Concepts of Bioinformatics (Paperback)

Bioinformatics is a burgeoning interdisciplinary field that holds great promise in handling large scale biomedical data by computational approaches. The book "Fundamental Concepts of Bioinformatics" is a very important textbook and reference book for both biology and computer science students and researchers, as well as for those professionals in medical science, and the pharmaceutical industry. It goes with saying that many laboratory approaches are expensive and time consuming, and cannot hope to keep up with the rapid growth of available data, making computational approaches indispensable. While a number of books dealing with bioinformatics, most of them are generally limited in scope, and very few of them provide a comprehensive but easy understandable treatment from both computer science and biomedical principles. This book is unique and is well-organized, and provides a systematic but straightforward treatment of the various techniques used for bioinformatics. One of the attractive features of the book is the comprehensive coverage of the various types of data use in bioinformatics analysis, followed by computational approaches that are most suited to the particular data type. This book also helps researchers entering bioinformatics. The reader can quickly identify the chapters that are most relevant to their own interest. It could also be used as a textbook for a senior undergraduate or a graduate level bioinformatics course. It is a valuable resource to both students and researchers, no matter whether they perform experimental research or computer science studies. Computer scientists, mathematicians, and statisticians seeking to discover how bioinformatics is related to well-defined paradigms in computer science could also benefit greatly from this book. Professors Michael L. Raymer and Dan E. Krane have authored many research articles in both computer science and biological science. I highly recommend this book as a great textbook and reference book for both students and researchers.

0 of 4 people found the following review helpful:

3.0 out of 5 stars Condition of book mislabeled?, July 25, 2010

By 

FFF - See all my reviews

Amazon Verified Purchase

This review is from: Fundamental Concepts of Bioinformatics (Paperback)

Condition was stated as like new condition with little highlighting. Well there was highlighting and writing all throughout the book. Book was in decent condition, just definitely not like new condition