Need to Return Your Textbook Rental?

Sorry, this item is not available in
Image not available for
Color:
Image not available

To view this video download Flash Player

 


or
Sign in to turn on 1-Click ordering
Sell Us Your Item
For a $25.79 Gift Card
Trade in
Kindle Edition
Read instantly on your iPad, PC, Mac, Android tablet or Kindle Fire
Buy Price: $49.99
Rent From: $14.48
Free Trial: $0.00
 
 
 
More Buying Choices
Have one to sell? Sell yours here

Fundamentals of Clinical Trials [Paperback]

Lawrence M. Friedman , Curt D. Furberg , David L. DeMets
5.0 out of 5 stars  See all reviews (8 customer reviews)

Buy New
$61.57 & FREE Shipping. Details
Rent
$23.68
In Stock.
Ships from and sold by Amazon.com. Gift-wrap available.
In Stock.
Rented by Renttext and Fulfilled by Amazon.
Want it tomorrow, July 11? Choose One-Day Shipping at checkout. Details
Free Two-Day Shipping for College Students with Amazon Student

Formats

Amazon Price New from Used from
 
Kindle Edition
Rent from
$49.99
$14.48
 
Paperback $61.57  
Up to 50% Off Select Medical Titles
For a limited time, enjoy special savings on select medical books from Springer. Learn more

Book Description

September 21, 2010 1441915850 978-1441915856 4th ed. 2010
This is the fourth edition of a very successful textbook on clinical trials methodology, written by three recognized experts who have long and extensive experience in all areas of clinical trials. Most chapters have been revised considerably from the third edition. A chapter on ethics has been added and topics such as noninferiority and adaptive designs now receive considerable discussion. There is much new material on adverse events, adherence, data monitoring, and issues in analysis. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials from a variety of medical disciplines to illustrate the fundamentals. The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan, and reporting the trial results according to the pre-specified objectives. Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the

Frequently Bought Together

Fundamentals of Clinical Trials + Conducting Clinical Research: A Practical Guide for Physicians, Nurses, Study Coordinators, and Investigators + Clinical Trials: Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines
Price for all three: $183.02

Buy the selected items together

Customers Who Bought This Item Also Bought


Editorial Reviews

Review

From the reviews of the fourth edition:

“This book is clearly written for students in the arena of health care. Physicians and health care providers can use it as a reference book. … The organization and structure is good and logical. … it deepens the understanding of applications of statistical methods and the analysis of clinical trials. Also, it provides a list of references at the end of each chapter. … In summary, this is an important contribution, providing up-to-date coverage on clinical trial methodology in a logical and systematic manner.” (Technometrics, Vol. 53 (2), May, 2011)

From the Back Cover

This is the fourth edition of a very successful textbook on clinical trials methodology, written by three recognized experts who have long and extensive experience in all areas of clinical trials. Most chapters have been revised considerably from the third edition. A chapter on ethics has been added and topics such as noninferiority and adaptive designs now receive considerable discussion. There is much new material on adverse events, adherence, data monitoring, and issues in analysis. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials from a variety of medical disciplines to illustrate the fundamentals. The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan, and reporting the trial results according to the pre-specified objectives. Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this text useful. This book has been successfully used for teaching courses in clinical trial methodology.

Product Details

  • Paperback: 400 pages
  • Publisher: Springer; 4th ed. 2010 edition (September 21, 2010)
  • Language: English
  • ISBN-10: 1441915850
  • ISBN-13: 978-1441915856
  • Product Dimensions: 9.2 x 6.2 x 0.9 inches
  • Shipping Weight: 1.5 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (8 customer reviews)
  • Amazon Best Sellers Rank: #81,691 in Books (See Top 100 in Books)

Customer Reviews

5.0 out of 5 stars
(8)
5.0 out of 5 stars
4 star
0
3 star
0
2 star
0
1 star
0
Most Helpful Customer Reviews
2 of 2 people found the following review helpful
5.0 out of 5 stars THE classic on trial management March 12, 2013
By biermam
Format:Kindle Edition
I attended Lawrence Friedman's course in clinical trial management at the Münster Epidemiology Summer school in two successive years because it was so good. The book is even better.
Comment | 
Was this review helpful to you?
2 of 2 people found the following review helpful
5.0 out of 5 stars Fundamentals of Clinical Trials February 21, 2013
Format:Paperback|Verified Purchase
Used this with my course on clinical research methods. Very exhaustive description of the details of clinical trial design, implementation, analysis and reporting. Recommended for any clinical researcher conducting or wanting to improve their knowledge of clinical trials.
Comment | 
Was this review helpful to you?
1 of 1 people found the following review helpful
5.0 out of 5 stars Easy to read January 18, 2014
Format:Kindle Edition|Verified Purchase
I found this book very easy to read and it gave many real life examples. I started with basically no experience or knowledge of the subject matter. I think it was an excellent introduction to the topic.
Comment | 
Was this review helpful to you?
0 of 1 people found the following review helpful
5.0 out of 5 stars THE classic on clinical trials May 4, 2013
Format:Kindle Edition|Verified Purchase
Lawrence Friedman is one of the world's leading authorities on clinical trials management. I have been using this book for years.
Comment | 
Was this review helpful to you?

What Other Items Do Customers Buy After Viewing This Item?


Forums

Have something you'd like to share about this product?
Start a new discussion
Topic:
First post:
Prompts for sign-in
 


Search Customer Discussions
Search all Amazon discussions


Look for Similar Items by Category


Want to discover more products? You may find many from participate in clinical trials shopping list.