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A Theory of the Basal Ganglia and Their Disorders (Conceptual Advances in Brain Research)
 
 
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A Theory of the Basal Ganglia and Their Disorders (Conceptual Advances in Brain Research) [Hardcover]

Robert Miller (Author)

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Book Description

August 8, 2007 1420058975 978-1420058970 1
The Basal ganglia, to adopt a phrase of Churchill's, are "a riddle wrapped in a mystery, inside an enigma." And although there is a wealth of information available on them, this research field remains controversial due in part to the diverse number of disciplines involved. A Theory of the Basal Ganglia and Their Disorders provides a clear, coherent view of basal ganglia that integrates evidence from the basic neurosciences, neurology, and psychiatry. The author explores the basal ganglia within a context of the function of the mammalian forebrain as a whole.

Divided into two parts, the book explores the basic framework in which normal functions of the basal ganglia can be understood, and then moves on to discuss major disorders. It explains, as far as possible, symptoms and related clinical facts in terms of the underlying pathology and pathophysiology. With this goal in mind, the author includes only disorders of the basal ganglia for which there are already clear ideas about the underlying neuropathology or pathophysiology. He also conveys the human experience of these disorders as well as their scientific basis.

While many books cover cutting-edge research, none have addressed large-scale questions about the role of the basal ganglia as a whole. Until now. This is arguably the only book published in the last 50 years that has attempted to provide an overall theory of the basal ganglia, as well as relevant areas of neurology and psychiatry. It concisely presents the theory, rather than comprehensively covering all the literature, and places the essential clinical facts within a framework formulated for normal operations of the basal ganglia. Presenting a unified view, the book takes several steps toward unraveling the riddle that is basal ganglia.

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University of Otago, Dunedin, New Zealand

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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
basal ganglia output, prolonged underactivity, striatal principal cells, basal ganglionic function, striatal cholinergic cells, dopaminergic reinforcement, striatal units, dopaminergic dyskinesias, many striatal neurons, motor thalamus, bouton counts, dopaminergic underactivity, hyperkinetic ones, classic motor symptoms, pathways from striatum, different functional circuits, rat pallidum, focused stereotypy, supersensitivity psychosis, dopamine states, output nuclei, medium spiny cells, chronic regimes, adventitious reinforcement, multiterminal innervation
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Syndromes Arising, Complications of Prolonged Underactivity, Theories of Basal Ganglionic Function, Dopamine-Dependent Psychosis, Oliver Sacks, Brain Res, Dynamics of the Basal Ganglia, Predictions Derived, Function Studied, Wiley Agency, Wylie Agency, Dorland's Illustrated Medical Dictionary, Akinesia Direct
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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