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Gene Cloning and DNA Analysis: An Introduction
 
 
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Gene Cloning and DNA Analysis: An Introduction [Illustrated] [Paperback]

T. A. Brown (Author)
4.8 out of 5 stars  See all reviews (4 customer reviews)


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Gene Cloning and DNA Analysis: An Introduction (Brown, Gene Cloning and DNA Analysis) Gene Cloning and DNA Analysis: An Introduction (Brown, Gene Cloning and DNA Analysis) 5.0 out of 5 stars (4)
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Book Description

063205901X 978-0632059010 October 15, 2001 4
The previous edition of Gene Cloning, has become known world-wide as the standard introductory text to this important and exciting subject. Now, the current importance of non-cloning approaches, notably PCR, in gene cloning has led to the creation of this fourth edition which explores DNA analysis.

Retaining the philosophy of the previous editions, Gene Cloning and DNA Analysis assumes the reader has little prior knowledge of the subject and clearly explains its importance, the principles of the techniques used and their applications. It is carefully laid out, with over 250 two-colour illustrations. In addition to some organisational changes within the re-written text, the fourth edition has two new chapters. The first covers the methods used to sequence genomes and how to understand a sequence after it has been obtained. The second looks in detail at the applications of gene cloning and DNA analysis in forensic science; providing an excellent illustration of the applications of DNA analysis in the real world.

In Gene Cloning and DNA Analysis Terry Brown has once again provided a resource of exceptional clarity, an essential introductory text to a wide range of biological sciences students, including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. Also, as well as being required reading for many course modules, it is a perfect introductory text for any professional who needs to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied or taught should have multiple copies of the book available on their shelves.


Terry Brown is Professor of Biomolecular Archaeology at the Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, Manchester, UK.

Visit the companion website for more details about the book:

http://www.blackwellpublishing.com/genecloning/


  • Fourth edition of internationally popular undergraduate text.
  • Terry Brown is world famous for his work and writing in the area of genomes, genetics and gene cloning.
  • Fully updated and revised.
  • Two-colour text including approximately 250 two-colour line illustrations.
  • New dedicated web pages for the book, including student questions, illustrations and supplementary material.


Editorial Reviews

Book Description

Explaining the significance, the principles, the techniques, and the applications of gene cloning and DNA analysis, this introduction assumes little prior knowledge on the part of the reader. Particular attention is given to the methods of sequencing genomes and analyzing this sequence. The applications to forensics science are highlighted. Approximately 250 color illustrations are featured. Brown teaches biomolecular archeology at UNMIST. Annotation c. Book News, Inc., Portland, OR (booknews.com)

From the Back Cover

The previous edition of Gene Cloning, has become known world-wide as the standard introductory text to this important and exciting subject. Now, the current importance of non-cloning approaches, notably PCR, in gene cloning has led to the creation of this fourth edition which explores DNA analysis.

Retaining the philosophy of the previous editions, Gene Cloning and DNA Analysis assumes the reader has little prior knowledge of the subject and clearly explains its importance, the principles of the techniques used and their applications. It is carefully laid out, with over 250 two-colour illustrations. In addition to some organisational changes within the re-written text, the fourth edition has two new chapters. The first covers the methods used to sequence genomes and how to understand a sequence after it has been obtained. The second looks in detail at the applications of gene cloning and DNA analysis in forensic science; providing an excellent illustration of the applications of DNA analysis in the real world.

In Gene Cloning and DNA Analysis Terry Brown has once again provided a resource of exceptional clarity, an essential introductory text to a wide range of biological sciences students, including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. Also, as well as being required reading for many course modules, it is a perfect introductory text for any professional who needs to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied or taught should have multiple copies of the book available on their shelves.


Product Details

  • Paperback: 363 pages
  • Publisher: Wiley-Blackwell; 4 edition (October 15, 2001)
  • Language: English
  • ISBN-10: 063205901X
  • ISBN-13: 978-0632059010
  • Product Dimensions: 9.7 x 7.5 x 0.8 inches
  • Shipping Weight: 2 pounds
  • Average Customer Review: 4.8 out of 5 stars  See all reviews (4 customer reviews)
  • Amazon Best Sellers Rank: #865,153 in Books (See Top 100 in Books)

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Customer Reviews

4 Reviews
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Average Customer Review
4.8 out of 5 stars (4 customer reviews)
 
 
 
 
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29 of 29 people found the following review helpful:
5.0 out of 5 stars A Versatile, Accessible Introduction, October 13, 2001
This review is from: Gene Cloning and DNA Analysis: An Introduction (Paperback)
I came away very impressed from Dr. Brown's latest edition. The book is extremely readable but does not dumb down the material. I'm taking an upper-level molecular genetics lab and am doing independent work in genetics, and this book is a great reference. However, I think that this book would be pretty easy for someone with introductory level biology--heck, I think some AP Biology high school teachers may be able to use this text for their classes.

Brown takes you through all the basics of molecular genetics: from the basic mechanics of DNA manipulation to PCR, bacteriophages, and even a review of basic genomics and genomic analysis, which are still very new and rapidly evolving fields. Every chapter has references for more in-depth study. This is a great book to introduce you to modern molecular genetics.

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13 of 13 people found the following review helpful:
5.0 out of 5 stars A Good Book for Introductory Courses in Molecular Biology, December 31, 2004
This review is from: Gene Cloning and DNA Analysis: An Introduction (Paperback)
I am a science student Studying Biochemistry and Molecular Biology. I used this book as a reference book for an Introduction to Genetic Engineering course. It was a great help for me. The book outlines the basic principles and methods in many aspects of Molecular Biology and Genetic Engineering in the simplest of ways. The book is easy to understand even to people with no big background in Molecular Biology as it explains everything from zero. It is a great book for introductory courses or as a quick reference for the basic ideas of some techniques and advances in the field. It does not give a lot of detail and explanation that is usually required from university students, such as myself, so more in-depth references are certainley required. However, as a joyful read for those interested in the field, or simply as a quick revision of the basics before your final exam, this book works wonders! Trust me... I got a straight A (99% on my final) :) All in all, it's a good book!
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4 of 4 people found the following review helpful:
4.0 out of 5 stars clearly written undergraduate text, November 29, 2006
As an introductory text on its subject, the book is well written. With copious diagrams that are easy to understand and that illustrate key ideas. A merit of the book is the clarity of the textual exposition, reinforced by those diagrams.

The text is also quite up to date in this fast changing field. With the good coverage of many topics. Including the seminal Polymerase Chain Reaction, that is the basis of so much else. You can see that genomics/biotechnology is now a practical and quantitative science. With plenty remaining to be understood, to be sure. But the book shows that we now have powerful tools to experiment with, to reduce our ignorance.
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Inside This Book (learn more)
First Sentence:
"In the middle of the nineteenth century, Gregor Mendel formulated a set of rules to explain the inheritance of biological characteristics." Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
gene subtraction, clone contig approach, clone contig assembly, recombinant protein synthesis, clone large pieces, hybridization probing, heterologous probing, lytic infection cycle, gene cloning experiment, mapping reagent, new phage particles, studying genomes, cloning vectors, cos sites, recombinant protein production, clone identification, artificial gene, insertional inactivation, kanamycin resistance gene, vector molecule, cloned gene, marker rescue, yeast vector, replacement vector, vitro packaging
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Manipulation of Purified, Nucleic Acids Research, Journal of Molecular Biology, Scientific Publishers, Current Opinion, Nature Biotechnology, Nature Genetics, Tsar Nicholas
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