Gene Genealogies, Variation and Evolution: A Primer in Coalescent Theory [Paperback]

Jotun Hein (Author), Mikkel H. Schierup (Author), Carsten Wiuf (Author)

Book Description

ISBN-10: 0198529961 | ISBN-13: 978-0198529965 | Publication Date: February 17, 2005 | Edition: 1

Coalescent theory tells us what gene genealogies are expected to look like if populations have different demographic histories - i.e, population size, structure, etc. The aim of this book is to provide an accessible introduction to Coalescent Theory with a view towards data analysis. Coalescent Theory has in the last two decades moved from being an obscure technique that appealed to mathematical population geneticists to a central tool in data analysis of DNA sequences. The completion of the sequencing of the human genome and accompanying determination of SNPs and haplotypes will increase its importance even further. This textbook, rich in examples and illustrations, is suitable for a graduate course in statistics, population-, molecular-, and medical genetics.

Editorial Reviews

Review

"There has been a dire need for a good book introducing coalescent theory to biologists. Gene Genealogies, Variation and Evolution fills this important gap this book should be mandatory reading for any graduate student working on population-level molecular data."-Evolution

About the Author

Jotun Hein is a Professor of Bioinformatics Department of Statistics, University of Oxford. Mikkel Schierup and Carsten Wiuf are both at the Bioinformatics Research Center, University of Aarhus, Denmark.

Product Details

• Paperback: 290 pages
• Publisher: Oxford University Press, USA; 1 edition (February 17, 2005)
• Language: English
• ISBN-10: 0198529961
• ISBN-13: 978-0198529965
• Product Dimensions: 9.6 x 6.7 x 0.7 inches
• Shipping Weight: 1.4 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #1,150,760 in Books (See Top 100 in Books)

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