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Gene Therapy, Volume 40 (Advances in Pharmacology)
 
 
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Gene Therapy, Volume 40 (Advances in Pharmacology) [Hardcover]

J. Thomas August (Editor), Ferid Murad (Series Editor), M. W. Anders (Series Editor), Joseph T. Coyle (Series Editor)

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Book Description

July 9, 1997 0120329417 978-0120329410 1
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. Volume 40, GeneTherapy, features important new research on gene transfers and therapy in the herpes simplex virus, anti-tumor immunity, steroid receptors, cystic fibroses, and more.

Key Features
* It provides an excellent overview on a series of topics on gene therapy for the serious investigator

Editorial Reviews

Review

Praise for the Serial
"Recommended not only to pharmacologists but also to all those in related disciplines."
--NATURE
"The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated."
--H.E. Kaufmann in CHEMOTHERAPY
"Superb reading material."
--JOURNAL OF PHARMACEUTICAL SCIENCES
Praise for the Volume
"This volume is intended for the reader with considerable background, experience, training, and knowledge in the field of gene therapy... is well written, comprehensive, and informative."
--Eugene Pergament, Northwestern University Medical School, DODDY REVIEW.

From the Back Cover

Praise for the Series
"Recommended not only to pharmacologists but also to all those in related disciplines."
--NATURE
"The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated."
--H.E. Kaufmann in CHEMOTHERAPY
"Superb reading material."
--JOURNAL OF PHARMACEUTICAL SCIENCES
Gene therapy has rapidly become a new frontier in pharmacology and experimental therapeutics. An explosion of interest in the identity, structure and function of genes, the mapping of the human genome, and the realization of the genetic basis of many diseases has been the genesis of a new paradigm in medical research-that of genetic medicine.
Inevitably, studies of the genetic bases of disease and the application of gene therapy to disease processes will lead to new discoveries for disease control. The evolution of gene therapy includes not only identification of genes and gene products, but also of mechanisms for delivery and for regulation of gene expression. Advanced programs already exist for the treatment of many disease processes including blood clotting disorders, anemias, growth deficiency, liver function, cancer, neurological abnormalities, cardian malfunction, obesity, vision, and a host of genetic diseases.
This volume of Advances in Pharmacology features important new research on gene transfers and therapy in the herpes simplex virus, anti-tumor immunity, steroid receptors, cystic fibroses, and more.

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Inside This Book (learn more)
First Sentence:
Clearly, the antisense concept derives from an understanding of nucleic acid structure and function and depends on Watson-Crick hybridization (Watson and Crick, 1953). Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
tumor cell eradication, tumor suppressor gene therapy, cationic immunoliposomes, transduced tumor cells, allogeneic melanoma cells, suppressor resistance, irradiated tumor cells, immunogene therapy, free dox, immunoliposome design, modified tumor cells, murine breast cancer model, systemic gene therapy, nonantisense effects, antisense mechanism, cancer gene therapy, ovarian carcinoma cell line, phosphorothioate oligonucleotides, retinoblastoma protein expression, antisense research, autologous tumor cells, nuclease stability, transduced cells, cytokine gene transfer, stabilized liposomes
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Gene Ther, Cancer Res, Nucleic Acids Res, Boca Raton, New York, Cancer Inst, Academic Press, Intracerebral Rat, National Institutes of Health, Antisense Res, Cell Mol, The Netherlands, San Diego, San Francisco, Akira Irie, Cell Biol, Genes Dev, Raven Press, Brain Res, Cancer Therapeutics, Study of Autologous, Cell Growth Differ, Johns Hopkins, Lipofection Phase, Steroid Biochem
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