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The Genetic Basis of Human Cancer
 
 
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The Genetic Basis of Human Cancer [Hardcover]

Bert Vogelstein (Author), Kenneth W. Kinzler (Author)
5.0 out of 5 stars  See all reviews (1 customer review)


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Book Description

March 19, 2002

Reveals what leading experts have recently discovered about cancers caused by DNA alterations!

The second edition of THE GENETICS OF CANCER, newly titled THE GENETIC BASIS OF HUMAN CANCERS, updates and informs on the most recent progress in genetic cancer research and its impact on patient care. With contributions by the foremost authorities in the field, this fascinating new edition reports on how to understand and predict tumor development - information that can enhance decision-making and advance genetic research.

2ND Edition Highlights

NEW CHAPTERS:
* Peutz-Jeghers syndrome
* Juvenile polyposis syndrome
* Tumor genome instability
* Gene expression profiling in cancer
* Pilomatricoma and pilomatrix carcinoma
* Hereditary paragangliomas of the head and neck
* Cylindromatosis
* Familial cardiac myxomas and carney complex
* Cancers of the oral cavity and pharynx
* Genetic abnormalities in lymphoid malignancies

THOROUGHLY REVISED:
* Every chapter has been meticulously reviewed and revised to incorporate the most recent research and clinical findings
* Includes a valuable introduction by renowned editors Vogelstein & Kinser
* Features 150 MORE illustrations than the previous edition


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Editorial Reviews

About the Author

BERT VOGELSTEIN, MD, Investigator, Howard Hughes Medical Institute, Clayton Professor of Oncology and Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland KENNETH W. KINZLER, PhD, Professor of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland

Product Details

  • Hardcover: 821 pages
  • Publisher: McGraw-Hill Professional; 2 edition (March 19, 2002)
  • Language: English
  • ISBN-10: 0071370501
  • ISBN-13: 978-0071370509
  • Product Dimensions: 11 x 8.6 x 1.3 inches
  • Shipping Weight: 4.4 pounds
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #1,211,906 in Books (See Top 100 in Books)

 

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2 of 2 people found the following review helpful:
5.0 out of 5 stars Thumbs up., June 13, 2003
By 
Ahmed Fazly (Winona, MN United States) - See all my reviews
This review is from: The Genetic Basis of Human Cancer (Hardcover)
Great text for any graduate student to get an understanding of the genetics of cancer. This book has something in it for everybody and is divided into the following areas: Basic concepts, cell cycle control, familial cancer syndromes and cancers by site.

It is a great text for a graduate student interested in cancer and does proved a very extensive introduction for an advanced student. It is an excellent source of reviews for a graduate student. It's of course not recommended for any lay audience. I use it often as great reference. The drawback is that it is not a good introductory text but one that would help you build upon your previous understanding and looks at the subject area quite in-depth.

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Inside This Book (learn more)
First Sentence:
As late as the 1970s, human cancers remained a black box. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
familial cylindromas, enteropancreatic neuroendocrine tumors, familial pilomatricomas, endometrial intraepithelial carcinoma, landscaper defects, sporadic pancreatic cancer, neurofibromin expression, familial pancreatic cancer, cervical tumorigenesis, cancer gene testing, pilomatrix carcinoma, homologous unequal recombination, gene test results, somatic cell genetic studies, prolactinoma variant, desmoplastic small round cell tumor, familial cylindromatosis, uterine serous, cancer gene tests, primary bladder tumors, familial neuroblastoma, amplified domain, carney complex, atm knockout mice, gastric tumorigenesis
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Hum Genet, Proc Natl Acad Sci, Nature Genet, New York, Mol Cell Biol, Med Genet, United States, Biol Chem, Genes Dev, Clin Oncol, Nucleic Acids Res, Proc Nail Acad Sci, Clin Endocrinol Metab, Proc Nall Acad Sci, Ashkenazi Jewish, Hum Mol Genet, Cancer Genet Cytogenet, Genes Chromosomes Cancer, Cancer Genet Cvtogenet, Clin Invest, Nail Cancer, Mal Cell Biol, Ann Intern Med, Genes Chromosom Cancer, Nature Med
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