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Genetic Dissection of Complex Traits, Volume 42 (Advances in Genetics)
 
 
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Genetic Dissection of Complex Traits, Volume 42 (Advances in Genetics) [Hardcover]

D. C. Rao (Editor)
5.0 out of 5 stars  See all reviews (2 customer reviews)

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There is a newer edition of this item:
Genetic Dissection of Complex Traits, Volume 60, Second Edition (Advances in Genetics) Genetic Dissection of Complex Traits, Volume 60, Second Edition (Advances in Genetics)
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Book Description

October 18, 2000 0120176424 978-0120176427 1
Genetic Dissection of Complex Traits will present the full range of methodologies that are essential for understanding the basis of human genetic disorders, the origin of such diseases, and theories on how to determine one's genetic predisposition to certain genetic diseases.

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Editorial Reviews

Review

"Genetic Dissection of Complex Traits provides an extensive overview of contemporary methods for statistical gene mapping."
—Alexandre A. Todorov for AMERICAN JOURNAL OF HUMAN GENETICS (July 2002)

From the Back Cover

This volume presents a long-awaited collection of state-of-the-art methods and strategies for the genetic dissection of complex human diseases and disease-related risk factors. Written by the world's leading experts in genetic epidemiology, this inspirational volume provides insights into emerging new methods and ideas on how best to tackle the impending challenges of the new millenium. These futuristic methods will help fulfill the promise of the Human Genome Project by optimizing our ability to locate these genes. In time, genetic dissection of the major human disease traits will facilitate development of custom-tailored pharmacogenetic treatments. An authentic compilation of these evolving methods has been sorely lacking, and this volume fills that void with multiple approaches to very controversial issues.

Product Details

  • Hardcover: 583 pages
  • Publisher: Academic Press; 1 edition (October 18, 2000)
  • Language: English
  • ISBN-10: 0120176424
  • ISBN-13: 978-0120176427
  • Product Dimensions: 9 x 6.1 x 1.5 inches
  • Shipping Weight: 1.8 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (2 customer reviews)
  • Amazon Best Sellers Rank: #3,432,534 in Books (See Top 100 in Books)

 

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1 of 1 people found the following review helpful:
5.0 out of 5 stars Collection of Genetic Epidemiological Developments, February 20, 2001
By A Customer
This review is from: Genetic Dissection of Complex Traits, Volume 42 (Advances in Genetics) (Hardcover)
There has been a lot of development of novel statistical methods in the last decade which has resulted in a better understanding of genetic disorders. There are not many existing books on the subject. This volume is a collection of excellent papers written by some of the renowned experts in the field. The papers range from the basic concepts in genetic epidemiology to applications of some of the most recently developed statistical techniques like CART . The precautions that one needs to take while analyzing genetic data have also been addressed in details. The final chapter by Newton Morton is a treat to read and provides a great overview of the future directions in the field. Overall the book will be very helpful to all genetic epidemiologists in their research.
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5.0 out of 5 stars great collection of statistical genetic techniques, May 22, 2002
By A Customer
This review is from: Genetic Dissection of Complex Traits, Volume 42 (Advances in Genetics) (Hardcover)
This book is great because it covers all the bases in statistical genetics and features authors who are some of the founders in the field. My favorite chapter is on the Newton Morton number - mine is 2 :) Definitely a good read for anyone interested in a growing field.
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Inside This Book (learn more)
First Sentence:
I first heard about Newton Morton from a graduate school classmate, Gordon Mainland, who was on the faculty of the University of Hawaii. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
discordant relative pairs, sibpair data, disease locus genotypes, robust lod score, trait locus genotypes, variance component linkage analysis, generalized relative risk ratios, localizing disease genes, sibpair design, lod score function, multivariate phenotype, test locus, allele sharing probabilities, recursive partitioning models, global search designs, lod score method, affected sibpairs, genotyping accuracy, assessing genetic linkage, disease gene location, maximal heritability, concordant sibpairs, lod curves, measured genotype information, mod score
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Academic Press, Newton Morton, Discussion References, Van Eerdewegh, National Institutes of Health, Cell Genet, American Psychiatric Press, Case Western Reserve University, Family Heart Study, Mental Disorders, San Francisco, Allan Award, Cambridge University Press, Genome Res, Monte Carlo, Genetic Analysis Workshop, John Wiley, National Institute of General Medical Sciences, Analysis of Human Genetic Linkage, Blood Institute, Conclusions References, Excerpta Medica, Johns Hopkins University Press, Jurg Ott
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