This comprehensive reference for novice students and experienced scientists studying DNA in organisms compares and evaluates the technological choices available in detecting genetic variances in pharmacogenomics. Commonly used technologies such as sequencing, DNA array and chip technologies, mass spectrometry, gel- and chromatography-based technologies, as well as less commonly used methods are described in detail and illustrated with specific examples. Expert advice is presented on technological options to facilitate decisions about the utility and applicability of individual technologies for specific needs.
Book Description
Editorial Reviews
Review
An essential contribution to the field of mutation discovery and genotyping. A reference guide for every molecular biology laboratory. --Norbert Arnold, Professor Dr. rer. nat.
About the Author
Karl H. Hecker, PhD, is a staff scientist with PerkinElmer Corporation. His other book is "Genetic Variance Detection - the nuts & bolts of DHPLC in Genomics"..
Product Details
Would you like to update product info or give feedback on images?
|
Customer Reviews
|
There are no customer reviews yet.
|
|||
|
Video reviews
|
Inside This Book
(learn more)
First Sentence:
The primary purpose of this chapter is to describe the instrument, software, and chemistry of the TRUGENE® DNA analysis platform. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
genetic variance detection, mismatch repair detection, primer annealing time, zebra fish mutant, basecalling accuracy, genotyping kit, differential sequencing, peak morphology, temperature gradient capillary electrophoresis, reverse transcriptase regions, genotype calls, homozygous control, primer annealing step, amplification bias, heterozygous samples, primer extension step, primary probe, genotyping data, genotyping assay, mutation scanning, mismatch site, genomic template, genotype identification, bead arrays, assay optimization Key Phrases - Capitalized Phrases (CAPs): (learn more)
Genome Res, Proc Natl Acad Sci, Nucleic Acids Res, Sequencing System, San Diego, Hum Genet, Third Wave Technologies, Mol Biol, Optimase Polymerase, Amersham Biosciences, Anal Biochem, Applied Biosystems, Clin Chem, Hum Mutat, Molecular Probes, Roche Amplicor, School of Medicine, Sentrix Array Matrix, Southampton University Hospital, State College, Biosearch Technologies, Clin Microbiol, Duthie Building, Epoch Biosciences, Genetic Analyzer New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
The primary purpose of this chapter is to describe the instrument, software, and chemistry of the TRUGENE® DNA analysis platform. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
genetic variance detection, mismatch repair detection, primer annealing time, zebra fish mutant, basecalling accuracy, genotyping kit, differential sequencing, peak morphology, temperature gradient capillary electrophoresis, reverse transcriptase regions, genotype calls, homozygous control, primer annealing step, amplification bias, heterozygous samples, primer extension step, primary probe, genotyping data, genotyping assay, mutation scanning, mismatch site, genomic template, genotype identification, bead arrays, assay optimization Key Phrases - Capitalized Phrases (CAPs): (learn more)
Genome Res, Proc Natl Acad Sci, Nucleic Acids Res, Sequencing System, San Diego, Hum Genet, Third Wave Technologies, Mol Biol, Optimase Polymerase, Amersham Biosciences, Anal Biochem, Applied Biosystems, Clin Chem, Hum Mutat, Molecular Probes, Roche Amplicor, School of Medicine, Sentrix Array Matrix, Southampton University Hospital, State College, Biosearch Technologies, Clin Microbiol, Duthie Building, Epoch Biosciences, Genetic Analyzer New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
Citations (learn more)
This book cites 2
books:
- Mutation Detection by Richard G. H. Cotton in Front Matter, and page 83
- University Hospital 1 by Cherie Bennett on page 145
Books on Related Topics
(learn more)
|
Tag this product(What's this?)Think of a tag as a keyword or label you consider is strongly related to this product.
Tags will help all customers organize and find favorite items. |
Sell a Digital Version of This Book in the Kindle Store
If you are a publisher or author and hold the digital rights to a book, you can sell a digital version of it in our Kindle Store.
Learn more
Customer Discussions
|
This product's forum
Active discussions in related forums
Search Customer Discussions
|
Related forums
|
