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Genome Evolution: Gene and Genome Duplications and the Origin of Novel Gene Functions
 
 
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Genome Evolution: Gene and Genome Duplications and the Origin of Novel Gene Functions [Hardcover]

Axel Meyer (Editor), Yves van de Peer (Editor)

Price: $149.00 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

April 30, 2003
In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances. This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context, provide evidence regarding the relative importance of gene duplication. The alternative explanation is that the evolution of regulatory elements that control the expression of and interactions among genes has been a more important force in shaping evolutionary innovation. This collection of papers will be of interest to all academic and industry researchers working in the fields of molecular biology, biotechnology, genomics and genome centers.

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Inside This Book (learn more)
First Sentence:
A very reasonable, albeit unproven scenario, maintains that early cellular life went through a stage in which RNA macromolecules constituted the major biopolymers (Woese, 1967; Crick, 1968; Orgel, 1968). Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
genome duplication hypothesis, endomesodermal specification, positive selection sites, brachvurv expression, bigene clusters, paralogous regions, block duplications, codon models, paralogy groups, duplicated blocks, paralogous chromosomal regions, novel gene functions, cated genes, genome doubling, genome duplication event, gene duplicates, genome duplications, lens expression, divergent resolution, genome fusion, primordial sex, expression territories, extensive gene duplication, crystallin genes, duplication history
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Genome Res, Nucleic Acids Res, Trends Genet, Cell Biol, International Human Genome Sequencing Consortium, Maynard Smith, Oxford University Press, Darwinian Threshold, Kluwer Academic Publishers, Susumu Ohno, Academic Press, Cure Opin, Dec Biol, New Haven, Van Tol, Cambridge University Press, Cell Der, Nature Genet, Plant Cell, Sinauer Associates, Cure Biol, Genoine Res, Princeton University Press, References Adams
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