The 2003 completion of the Human Genome Project was just one step in the evolution of DNA sequencing. Now from a "who's who" of pioneers in the field comes the latest genome sequencing and assembly advances that are redefining the field. This trail-blazing book gives researchers, unparalleled access to state-of-the-art DNA sequencing technologies, new algorithmic sequence assembly techniques, and emerging methods for both resequencing and genome analysis that together form the most solid foundation possible for tackling experimental and computational challenges in the genome sciences today. Including critiques of existing techniques, this far-reaching resource offers researchers assistance in achieving more rapid and accurate DNA sequencing and developing the next generation of high-throughput methods and devices.
Genome Sequencing Technology and Algorithms
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About the Author
Sun Kim is assistant professor and associate director of bioinformatics at Indiana University's Center for Genomics and Bioinformatics. Dr. Kim earned his Ph.D. in Computer Science at the University of Iowa. Elaine R. Mardis is assistant professor at Washington University School of Medicine and co-director of the university's Genome Sequencing Center. She received her Ph.D. in biochemistry from the University of Oklahoma. Haixu Tang is an assistant professor of informatics at Indiana University. He received his Ph.D. in computational biology from the Shanghai Institute of Biochemistry, China.
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Key Phrases - Statistically Improbable Phrases (SIPs):
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human genome, comparative sequencing, fragment assembly algorithms, polony sequencing, polymerase colonies, human epigenome project, genome sequencing technology, contig edges, mating node, partial haplotype completion, positional hashing, contig orientation, misassembled regions, pedigree graph, haplotyping problem, next generation sequencing technologies, haplotype inference problem, repeat contigs, resequencing arrays, shotgun data, mating loops, genome resequencing, tumor genome, fragment assembler, reference human genome Key Phrases - Capitalized Phrases (CAPs): (learn more)
Genome Res, Genome Sequencing, The Haplotyping Problem, Nucleic Acids Res, Complex Path, Overview of Genome Assembly Techniques, The Role, Human Disease, High-Throughput Assessments, Journal of Computational Biology, Analysis of Genomic Alterations, Cancer Res, Cell Biol, United States, Computational Molecular Biology, Sequencing Technology, New York, The International, Real-Time Pyrophosphate, Life Sciences, Sequencing Method Based, Combinatorial Pattern Matching, Microfabricated High-Density Picolitre Reactors, Cell Vol, Annual Conference Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
human genome, comparative sequencing, fragment assembly algorithms, polony sequencing, polymerase colonies, human epigenome project, genome sequencing technology, contig edges, mating node, partial haplotype completion, positional hashing, contig orientation, misassembled regions, pedigree graph, haplotyping problem, next generation sequencing technologies, haplotype inference problem, repeat contigs, resequencing arrays, shotgun data, mating loops, genome resequencing, tumor genome, fragment assembler, reference human genome Key Phrases - Capitalized Phrases (CAPs): (learn more)
Genome Res, Genome Sequencing, The Haplotyping Problem, Nucleic Acids Res, Complex Path, Overview of Genome Assembly Techniques, The Role, Human Disease, High-Throughput Assessments, Journal of Computational Biology, Analysis of Genomic Alterations, Cancer Res, Cell Biol, United States, Computational Molecular Biology, Sequencing Technology, New York, The International, Real-Time Pyrophosphate, Life Sciences, Sequencing Method Based, Combinatorial Pattern Matching, Microfabricated High-Density Picolitre Reactors, Cell Vol, Annual Conference Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
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