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From Genome to Therapy: Integrating New Technologies with Drug Development - No. 229
 
 
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From Genome to Therapy: Integrating New Technologies with Drug Development - No. 229 [Hardcover]

Novartis Foundation (Author), J. Craig Venter (Author)

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Book Description

0471627445 978-0471627449 November 2000 1
This important and exciting work brings together a high-calibre group of experts to discuss the practical application of genomic information to the development of drugs. Recent technological advances have led to a rapid acceleration in our ability to gather genetic data. The complete genetic sequences are now known for several organisms and accelerated programmes are in place for sequencing many other genomes, including human. The speed with which complete sequencing can be accomplished will continue to increase as new technologies come online. In principle, the scope for developing new diagnostic techniques and drugs is now greater than at any time in human history, but the pathway from genetic information to usable drug is a long and complex one.

This major book covers such subjects as the current state of the art in squencing technology, the applications of these new technologies to sequencing the genomes of various organisms, and the challenge of proteomics. Additional contributions deal with legal and ethical implications of the new uses of genetic data, and functional genomics from the point of view of the pharmaceutical industry.

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Editorial Reviews

Review

"It does successfully convey to the reader areas of controversy" (Microbiology Today, November 2001)

"there are a number of nuggets in the book that make it worth a browse." (Pharmaceutical Physician, December 2001)

"I found this book fun to read." (Biochemistry & Molecular Biology Education, No.29 2001)

"Contributors...present 17 papers and the discussions they generated at the symposium." (SciTech Book News, Vol. 25, No. 4, December 2001)

From the Back Cover

Recent technological advances have led to a rapid acceleration in our ability to gather genetic data. The complete genetic sequences are now known to several organisms and accelerated programmes are in place for sequencing many other genomes, including human. The speed with which complete sequencing can be accomplished will continue to increase as new technologies come online. In principle, the scope for developing new diagnostic techniques and drugs is now greater than at any time in human history, but the pathway from genetic information to usable drug is a long and complex one.

This exciting book brings together a high-calibre group of experts to discuss the practical application of genomic information to the development of drugs. The subjects covered include the current state of the art in sequencing technology, the applications of these new technologies to sequencing the genomes of various organisms, and the challenge of proteomics. Additional contributions deal with legal and ethical implications of the new uses of genetic data, and functional genomes from the point of view of the pharmaceutical industry.

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Inside This Book (learn more)
First Sentence:
It is exciting that the Novartis Foundation 50th Anniversary meeting is being held on genomics. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
mutant map, rad proteins, deletion strains, probe pairs, lateral gene transfer, oligonucleotide arrays, polymorphic variation, expression monitoring, cell epitopes, functional genomics, microbial genomes
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Proc Natl Acad Sci, Patent Office, Nat Genet, Nat Biotechnol, Anal Chem, European Union, Genome Res, Nat Med, Novartis Found Symp, Nucleic Acids Res, Biol Chem, Drug Dev Res
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