Genomic Imprinting: Causes and Consequences [Hardcover]

R. Ohlsson (Editor), K. Hall (Editor), M. Ritzen (Editor)

Book Description

Publication Date: January 26, 1996 | ISBN-10: 0521472431 | ISBN-13: 978-0521472432 | Edition: 1

Genomic imprinting results in the preferential expression of one gene, depending on the parent of origin, and it is associated with several disease syndromes in humans. This book covers a wealth of research material on chromatin structure, epigenetics, clinical genetics, developmental biology, cancer, hypotheses of evolution, and the molecular basis of the imprinting process, which will help explain not only the mechanisms of genomic imprinting, but also its biological and medical consequences.

Editorial Reviews

Review

"The names of most of the contributors will be familiar to those who have followed the field, as will the subject matter of most of the papers. But this is unlikely to prevent the vast majority of readers from encountering a number of pleasant surprises...a major strength of this collection, for the student and the casually interested reader, is in the way the majority of contributors have summarized the results of many experiments in a few sentences...The conversational tone of the contributions further makes for entertaining reading." Carmen Sapienza, Science

"The 24 contributed chapters have considerable scope...a useful resource not only for those actually working in the area, but also for those who are not working in this field but who need to maintain some level of knowledge for educational purposes." Roger W. Melvold, Doody's Health Sciences Book Review Journal

"...a valuable resource....It should be useful to scientists new to the field and to those wanting a broad view of the various imprinted systems....the information and models that it contains will continue to guide research in this dynamic field." Fay L. Shamanski, American Journal of Human Genetics

Book Description

This significant new publication on genomic or parental imprinting has been prepared by an outstanding team of international authorities. Genomic imprinting results in the preferential expression of one allele, depending on the parent of origin. It is associated with several disease syndromes in humans. Interest in this area has expanded rapidly from the time when it was first recognised that some important hereditary characterisitics were not adequately explained by the Mendelian laws of inheritance. The chapters cover a wealth of material to help explain not only the mechanisms of genomic imprinting but its biological and medical consequences.

Product Details

• Hardcover: 392 pages
• Publisher: Cambridge University Press; 1 edition (January 26, 1996)
• Language: English
• ISBN-10: 0521472431
• ISBN-13: 978-0521472432
• Product Dimensions: 10 x 7.1 x 1 inches
• Shipping Weight: 2.1 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #4,023,040 in Books (See Top 100 in Books)