Doctors and Researchers Confirm Benefits of Glucosamine, Chondroitin, and MSM: The prestigious medical journal The Lancet published a research paper that investigated the long-term impact of glucosamine sulfate over a three-year period. This double blind placebo controlled study with a broad patient population of over 100 was published in January 2001, and it was the first study to document the long-term benefits of supplementation to support joint health. A study in May 2000, conducted by Jean-Yves Reginister, M.D., Ph.D., reported that patients taking glucosamine had far greater improvements in joint health than those who went without it. "MSM provides a good portion of the body's need for sulfur. Sulfur is an important building block. It is an important nutritional supplement that is safe and useful." -Dr. Stanley W. Jacobs, M.D., Oregon Health Sciences University Results of a double blind placebo controlled study [Busci and Poor, 1998] in which 85 patients received either 400mg of chondroitin sulfate twice daily, or placebo, showed a 69% improvement in those taking chondroitin sulfate (versus 32% improvement in the placebo group). Dr. Randy Rosier of the University of Rochester, New York, reports that most placebo-controlled clinical trials of glucosamine have reported beneficial effects.