"...the most up-to-date compilation available...should be an integral part of all institutional libraries...it is also highly recommended that individuals...maintain their own copy..." (Journal of Medicinal Chemistry, March 8, 2007)
"...continues to be a comprehensive guide to the techniques for the formation and cleavage of protective groups." (Journal of the American Chemical Society, January 31, 2007)
For more than twenty-five years, Protective Groups in Organic Synthesis has been the definitive guide for organic chemists in designing synthetic routes. Now in its fourth edition, the text continues to be a uniquely comprehensive and an indispensable reference for both synthetic organic and medicinal chemists who want to control the reactivity of the most common functional groups during a synthetic sequence.
The Fourth Edition includes significant developments in protective group chemistry since 1998. In addition to incorporating new protective groups now available to the synthetic organic chemist, such as the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines, the book also covers new techniques for the formation and cleavage of existing protective groups, providing the most relevant and useful examples to illustrate each methodology. The content is organized around the functional group to be protected (ethers, acids, carbonyl groups, amines, amides, phenols, etc.), and ranges from the simplest to the most complex highly specialized protective groups.
New features of the Fourth Edition include:
As a trained carbohydrate chemist, I deal with protecting groups on a daily basis, and "Greene's" is always on my desk. Read morePublished 7 months ago by Matt
I think this book should be required in every chemistry laboratory. Very thorough! The charts in the back of the book are especially helpful.Published 13 months ago by Alfio Fichera
it helps a lot in total synthesis and all other chemical applications related to specific synthesis and modifications of moleculesPublished 13 months ago by A. Anatoly
Peter's book is an excellent and essential handbook for all organic chemists. Everyone should have one in hand.Published on July 24, 2010 by M. H. Chen
If you're a synthetic chemist, you know you need this book.
It's well organised by functional group, though I could quibble with details as to orthogonal stability. Read more
Greene's Protective Groups in Organic Synthesis (Purchased on 10/02/2008)
by Peter G. M. Wuts
i'm do organic synthesis. i reference this one once a week on average. it's the first stop whenever a protecting group questions comes up.Published on August 30, 2007 by art vandelay
There are other protecting group books out there but I found this one to be the most comprehensive and easy to use.Published on April 26, 2006 by M. Jeffries-EL