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HPLC Columns: Theory, Technology, and Practice
 
 
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HPLC Columns: Theory, Technology, and Practice [Hardcover]

Uwe D. Neue (Author)

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Book Description

July 28, 1997 0471190373 978-0471190370 1
An in-depth guide to HPLC column technology High-performance liquid chromatography and its derivative techniques have become the dominant analytical separation tools in the pharmaceutical, chemical, and food industries; environmental laboratories; and therapeutic drug monitoring. Although the column is the heart of the HPLC instrument and essential to its success, until now, no book has focused on the theory and practice of column technology. HPLC Columns provides thorough, state-of-the-art coverage of HPLC column technology for the practicing technician and academician alike. Along with a comprehensive discussion of the chemical and physical processes of the HPLC column, it includes fundamental principles, separation mechanisms and available technologies, column selection criteria, and special techniques. Special features include:
* Comprehensive overview of state-of-the-art HPLC column technology
* Explanation of the underlying principles of HPLC columns
* Methods for selecting columns
* Practical advice on using and applying columns, including examples
* Section by M. Zoubair El Fallah on methods development
* Special techniques, including preparative chromatography, continuous chromatography, and the simulated moving bed
* Troubleshooting section
HPLC Columns helps laboratory practitioners make better choices in column selection, methods development, and troubleshooting: it is also an excellent textbook for graduate-level courses and HPLC short courses.

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From the Publisher

This book provides thorough, state-of-the-art coverage of HPLC column technology. Along with a comprehensive discussion of the chemical and physical processes of the HPLC column, it includes fundamental principles, separation mechanisms and available technologies, column selection criteria, and special techniques.

From the Back Cover

An in-depth guide to HPLC column technology High-performance liquid chromatography and its derivative techniques have become the dominant analytical separation tools in the pharmaceutical, chemical, and food industries; environmental laboratories; and therapeutic drug monitoring. Although the column is the heart of the HPLC instrument and essential to its success, until now, no book has focused on the theory and practice of column technology. HPLC Columns provides thorough, state-of-the-art coverage of HPLC column technology for the practicing technician and academician alike. Along with a comprehensive discussion of the chemical and physical processes of the HPLC column, it includes fundamental principles, separation mechanisms and available technologies, column selection criteria, and special techniques. Special features include:
* Comprehensive overview of state-of-the-art HPLC column technology
* Explanation of the underlying principles of HPLC columns
* Methods for selecting columns
* Practical advice on using and applying columns, including examples
* Section by M. Zoubair El Fallah on methods development
* Special techniques, including preparative chromatography, continuous chromatography, and the simulated moving bed
* Troubleshooting section
HPLC Columns helps laboratory practitioners make better choices in column selection, methods development, and troubleshooting: it is also an excellent textbook for graduate-level courses and HPLC short courses.

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Inside This Book (learn more)
First Sentence:
High-performance liquid chromatography (HPLC), together with its derivative techniques, is today the dominant analytical separation tool in many industries. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
extracolumn band spreading, lone silanols, anomer peaks, bridged silanols, effective plate count, interstitial fraction, radially compressed column, permanent pore structure, lengthy equilibration times, polymeric packings, chromatographic space, retention chromatography, mass overload, column backpressure, extracolumn effects, aminopropyl bonded phase, parent silica, hydrophilic interaction chromatography, inorganic packings, specific pore volume, hindered mass transfer, silanol activity, slurry solvent, starting mobile phase, isocratic chromatography
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Waters Corp, New York, Marcel Dekker, Chromatographic Science Series, Academic Press, International Symposium, Commonly Used Bonded Phases, San Francisco, Showa Denko
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