HPLC Made to Measure: A Practical Handbook for Optimization [Hardcover]

Stavros Kromidas (Editor)

Book Description

Publication Date: August 31, 2006 | ISBN-10: 352731377X | ISBN-13: 978-3527313778 | Edition: 1

The only topical HPLC book to focus on optimization, this volume addresses the needs of HPLC users who wish to constantly improve their methods, in particular in terms of throughput, accuracy and cost-effectiveness.
This handbook features contributions from such bestselling authors as John W. Dolan, Michael McBrien, Veronika R. Meyer, Uwe D. Neue, Lloyd R. Snyder, and Klaus K. Unger, as well as from scientists working for major companies, including Agilent, AstraZeneca, Merck, Schering, Tosoh Biosep, VWR, and Waters. It covers essential aspects of optimization in general, optimization in different LC-modi, hyphenated techniques and computer-aided optimization. The whole is rounded off with a section of user reports.

Editorial Reviews

Review

"A valuable text by any estimation, I would recommend it highly for hands-on users or managers directing a group of chromatographers toward more efficient and effective HPLC separations." (Journal of the American Chemical Society, February 21, 2007)

From the Back Cover

Alongside developing new ones, the optimization of existing methods is a key task in the HPLC laboratory. And a task that nowadays has to be solved increasingly fast and cost-efficiently.

This handbook provides well-founded assistance in better meeting this challenge. Internationally renowned authors cover both the general basics and strategies in optimization, as well as the specific aspects involved in such different methods as RP-HPLC, NP-HPLC, micro- and nano-HPLC, and hyphenated techniques, such as LC/MS. Nor are such topics as column selection and chiral separations left uncovered. Some of the contributions present applications using common optimization software, such as DryLab or ChromSword. All of the chapters concentrate on the essentials and are written in a practically oriented style, while their self-contained structure allows for targeted references.

Throughout the text, the authors offer concrete, practical tips as well as pertinent background information, together with insights into the optimization methods of seven major international companies from various sectors.
The whole is rounded off with real-life reports from experienced users coming from the different areas of application, in particular the life sciences, such as proteomics or drug development.

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Product Details

• Hardcover: 786 pages
• Publisher: Wiley-VCH; 1 edition (August 31, 2006)
• Language: English
• ISBN-10: 352731377X
• ISBN-13: 978-3527313778
• Product Dimensions: 7 x 1.8 x 9.6 inches
• Shipping Weight: 3.5 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #2,409,688 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

5.0 out of 5 stars Great book, February 28, 2010

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This review is from: HPLC Made to Measure: A Practical Handbook for Optimization (Hardcover)

This book is filled with helpful insight for method development and optimization. It is an asset to any chromatographer's library.