HPLC for Pharmaceutical Scientists (Hardcover)

by Yuri V. Kazakevich (Author), Rosario LoBrutto (Author)
Key Phrases: pharmaceutical scientists, monoisotopic mass, pharmaceutical preformulation, New York, Mass Spectrom, John Wiley (more...)

Editorial Reviews

Review
"...extremely useful and quite extensive in its coverage of the subject..." (Journal of the American Chemical Society, July 18, 2007)

Product Description
HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry.

In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided.

This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development.

The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.

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Product Details

• Hardcover: 1136 pages
• Publisher: Wiley-Interscience; 1 edition (January 2, 2007)
• Language: English
• ISBN-10: 0471681628
• ISBN-13: 978-0471681625
• Product Dimensions: 9.4 x 6.4 x 2.4 inches
• Shipping Weight: 3.8 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars See all reviews (1 customer review)
• Amazon.com Sales Rank: #66,818 in Books (See Bestsellers in Books)

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Customer Reviews

Most Helpful Customer Reviews

3 of 3 people found the following review helpful:

5.0 out of 5 stars excellent book, January 19, 2008

By	Leon - See all my reviews

This book covers the fundamentals of HPLC separation with the inclusion of most recent advancements in the areas, such as column technologies, UPLC and LC-NMR. I found this book is really useful in a sense it provides overviews in almost every stages in the drug industry from discovery and process development to formulation, drug metabolism, and commercialization. This directly helps me to work more effectively with analytical chemists from other functional areas. The authors surely understand what are the practical challenges that a bench analytical chemist is facing everyday and provide a lot of usful strategies such as method development recipe in chapter 8 to tackle the problems. Overview, I view this book as a great reference for HPLC separation and problem solving manual for the analytical chemists in pharmaceutical industry.