In this volume on the auto-immune haemolytic anaemias, the author has attempted to continue the story of their understanding and treatment from the point reached when Part II of the second edition of "The Haemolytic Anaemias" was published in 1962. The result has been a volume greatly increased in size, an increase reflecting the substantial advances that have taken place in the past 30 years in the understanding of the structure of antibodies and of the mechanism and regulation of their formation, as well as the genesis of auto-immune diseases. It also reflects the burgeoning understanding of the complexity of the human blood-group antigens and of the complement system and also of the way in which the body deals with antibody-affected erythrocytes.
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