Composed of contributions from an international team of leading researchers, this book pulls together the most recent research results in the field of cancer modeling to provide readers with the most advanced mathematical models of cancer and their applications. The topics included in the book cover oncogenetic trees, stochastic multistage models of carcinogenesis, effects of ionizing radiation on cell cycle and genomic instability, induction of DNA damage by ionizing radiation and its repair, epigenetic cancer models, bystander effects of radiation, multiple pathway models of human colon cancer, and stochastic models of metastasis.The book also provides some important applications of cancer models to the assessment of cancer risk associated with various hazardous environmental agents, to cancer screening by MRI, and to drug resistance in cancer chemotherapy. An updated statistical design and analysis of xenograft experiments as well as a statistical analysis of cancer occult clinical data are also provided. The book will serve as a useful source of reference for researchers in biomathematics, biostatistics and bioinformatics; for clinical investigators and medical doctors employing quantitative methods to develop procedures for cancer diagnosis, prevention, control and treatment; and for graduate students.
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oncogenetic trees, bladder cancer screening, oncogenetic tree model, epigenetic hypotheses, near empty state, bystander signaling, mixed scale models, multistage cancer models, field effect hypothesis, stochastic proliferation, mutant daughter cell, focal lesion data, stochastic system model, focal transections, gamma frailty model, unirradiated cells, involving multiple pathways, ith pathway, disseminated cancer cells, clonal expansion model, bystander cells, virtual cystoscopy, papilloma cells, additional gene copies, first malignant cell Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, New York, Cancer Models, Major Epigenetic Hypotheses of Carcinogenesis Revisited, Cancer Inst, Cancer Biology, Analysis of Occult Tumor Studies, Risk Anal, Distribution of the Sizes of Metastases, Cell Biol, Radiation-Induced Bystander Effects, Monte Carlo, Cancer Risk Assessment of Environmental Agents, Marcel Dekker, World Scientific, Academic Press, New Jersey, Modeling the Effects of Radiation, Stochastic Models of Carcinogenesis, Health Perspect, United States, Second Copy, Reconstruction Algorithm, Magnetic Resonance Imaging, Cell Prolif Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
oncogenetic trees, bladder cancer screening, oncogenetic tree model, epigenetic hypotheses, near empty state, bystander signaling, mixed scale models, multistage cancer models, field effect hypothesis, stochastic proliferation, mutant daughter cell, focal lesion data, stochastic system model, focal transections, gamma frailty model, unirradiated cells, involving multiple pathways, ith pathway, disseminated cancer cells, clonal expansion model, bystander cells, virtual cystoscopy, papilloma cells, additional gene copies, first malignant cell Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, New York, Cancer Models, Major Epigenetic Hypotheses of Carcinogenesis Revisited, Cancer Inst, Cancer Biology, Analysis of Occult Tumor Studies, Risk Anal, Distribution of the Sizes of Metastases, Cell Biol, Radiation-Induced Bystander Effects, Monte Carlo, Cancer Risk Assessment of Environmental Agents, Marcel Dekker, World Scientific, Academic Press, New Jersey, Modeling the Effects of Radiation, Stochastic Models of Carcinogenesis, Health Perspect, United States, Second Copy, Reconstruction Algorithm, Magnetic Resonance Imaging, Cell Prolif Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
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