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Fantastic, Detailed Facts Based On Medical Studies, January 22, 2011
This review is from: The Handbook of Clinically Tested Herbal Remedies 2 Volume set (Hardcover)
"First Few Pages of the Books Contents"
PART I: FUNDAMENTALS OF HERBAL MEDICINE
Chapter 1. History and Regulation of Botanicals
in the United States 3
Loren D. Israelsen
Marilyn Barrett
Introduction 3
History 3
DSHEA Explained 5
Drugs: OTC and Rx 10
Prospectus 11
Chapter 2. Product Definition Deficiencies in Clinical
Studies of Herbal Medicines 13
Varro E. Tyler
Chapter 3. Identifying and Characterizing Botanical
Products 23
Marilyn Barrett
Identifying Plants by Name 24
Means of Assuring Plant Identity 26
Preparations and Formulations 30
Dose 30
Bioavailability 30
Guidelines 31
Appendix: Preparations and Formulations 32
Chapter 4. Standardization of Botanical Preparations:
What It Does and Does Not Tell Us 37
Uwe Koetter
Marilyn Barrett
Introduction 37
Standardization of Therapeutic Activity 38
Standardization to Meet a Chemical Norm 39
Standardization As a Reflection of Quality
Assurance Programs 41
Guidance 43
Situation in the Marketplace 44
Perspective 45
Chapter 5. The Importance and Difficulty in Determining
the Bioavailability of Herbal Preparations 49
Anton Biber
Friedrich Lang
Chapter 6. "Borrowed Science" and "Phytoequivalence":
Can Two Herbal Products Be Judged Equivalent? 59
Marilyn Barrett
Chemical or Pharmaceutical Equivalency 61
62
Application of the Concepts, Ginkgo As an Example 63
Meta-Analyses 65
Perspective 66
Chapter 7. Determining Efficacy of Herbal Preparations 69
Tieraona Low Dog
Observational Medicine 70
"Evidence-Based" Medicine 71
Summary 74
Chapter 8. Evaluating Safety of Herbal Preparations 77
Ezra Béjar
Joseph M. Betz
Marilyn Barrett
Evaluation of Safety 78
Adverse Reactions 80
Adverse-Event Reporting Systems 81
Categorization According to the Degree of Safety 82
Product Quality As an Aspect of Safety 84
Contraindications 85
Drug-Herb Interactions 85
Improving Our Knowledge of Safety 87
Chapter 9. Conducting Clinical Trials on Herbal Dietary
Supplements in North America: Commercialization,
Confidence, and Conflicts 91
Anthony L. Almada
The Spirit to Sponsor: Is There an Adequate Economic
Incentive to Fund Research? 92
Extracting Value from Science 95
Competitor Kevlar: Preventing Piracy of Product-Specific
Data 96
How Much Data Is Enough? 100
We Have Data--Now What? 103
Who Has Science and How Did They Acquire It? 105
Conclusion 105
Chapter 10. Motives for Conducting Clinical Trials
on Botanicals in Europe: A Focus on Germany 107
Joerg Gruenwald
Stefan Spiess
Chapter 11. Pharmacopoeias and Botanical Monographs 115
Marilyn Barrett
Roy Upton
V. Srini Srinivasan
United States Pharmacopeia and National Formulary
(USP-NF) 116
American Herbal Pharmacopoeia (AHP) and Therapeutic
Compendium 118
European Pharmacopoeia (EP) 119
British Herbal Pharmacopoeia (BHP) and British Herbal
Compendium (BHC) 119
German Commission E 120
European Scientific Cooperative on Phytotherapy (ESCOP) 121
Chinese Pharmacopoeia 121
African Pharmacopoeia 122
The Pharmacopoeia of Japan 122
The Pharmacopoeias of India 123
World Health Organization (WHO) 123
Other Pharmacopoeias 124
Summary and Perspective 124
Sources of Pharmacopoeias 125
PART II: METHODS
Chapter 12. Methods of Product and Trial Inclusion
and Evaluation 129
Marilyn Barrett
Gathering Information on Products and Trials 129
Data on Products and Trials 134
Evaluation of Clinical Trial Quality 137
Chapter 13. Clinical Trial Reviewer's Guidance
and Checklist 141
Tieraona Low Dog
Levels of Evidence 141
Guidelines for Reviewer Checklist: Part I 142
Guidelines for Reviewer Checklist: Part II 144
Scoring 146
PART III: BOTANICAL PROFILES--
PRODUCT AND CLINICAL TRIAL INFORMATION
(Artichoke-Ginseng)
Single Herbs 151
Artichoke 151
Preparations Used in Reviewed Clinical Studies 151
Artichoke Summary Table 152
Summary of Reviewed Clinical Studies 153
Postmarketing Surveillance Studies 154
Adverse Reactions or Side Effects 154
Information from Pharmacopoeial Monographs 155
Details on Artichoke Products and Clinical Studies 157
Bilberry 163
Preparations Used in Reviewed Clinical Studies 163
Bilberry Summary Table 164
Adverse Reactions or Side Effects 167
Information from Pharmacopoeial Monographs 168
Details on Bilberry Products and Clinical Studies 171
Black Cohosh 185
Preparations Used in Reviewed Clinical Studies 185
Black Cohosh Summary Table 186
Summary of Reviewed Clinical Studies 187
Postmarketing Surveillance Studies 189
Adverse Reactions or Side Effects 189
Information from Pharmacopoeial Monographs 190
Details on Black Cohosh Products and Clinical Studies 194
Boxwood 207
Preparations Used in Reviewed Clinical Studies 207
Summary of Reviewed Clinical Studies 207
Boxwood Summary Table 208
Adverse Reactions or Side Effects 209
Details on Boxwood Products and Clinical Studies 210
Butterbur, Purple 213
Preparations Used in Reviewed Clinical Studies 213
Butterbur Summary Table 214
Summary of Reviewed Clinical Studies 215
Adverse Reactions or Side Effects 216
Information from Pharmacopoeial Monographs 216
Details on Butterbur Products and Clinical Studies 218
Cat's Claw 225
Preparations Used in Reviewed Clinical Studies 225
Cat's Claw Summary Table 226
Summary of Reviewed Clinical Studies 227
Adverse Reactions or Side Effects 227
Details on Cat's Claw Products and Clinical Studies 228
Chaste Tree 231
Preparations Used in Reviewed Clinical Studies 231
Chaste Tree Summary Table 232
Summary of Reviewed Clinical Studies 233
Postmarketing Surveillance Studies 235
Adverse Reactions or Side Effects 236
Information from Pharmacopoeial Monographs 236
Details on Chaste Tree Products and Clinical Studies 240
Cordyceps 255
Preparations Used in Reviewed Clinical Studies 255
Summary of Reviewed Clinical Studies 255
Cordyceps Summary Table 256
Adverse Reactions or Side Effects 258
Information from Pharmacopoeial Monographs 258
Details on Cordyceps Products and Clinical Studies 260
Cranberry 265
Preparations Used in Reviewed Clinical Studies 265
Summary of Reviewed Clinical Studies 265
Cranberry Summary Table 266
Adverse Reactions or Side Effects 267
Information from Pharmacopoeial Monographs 268
Details on Cranberry Products and Clinical Studies 270
Devil's Claw 277
Preparations Used in Reviewed Clinical Studies 277
Summary of Reviewed Clinical Studies 277
Devil's Claw Summary Table 278
Adverse Reactions or Side Effects 280
Information from Pharmacopoeial Monographs 280
Details on Devil's Claw Products and Clinical Studies 283
Dragon's Blood Croton 291
Preparations Used in Reviewed Clinical Studies 291
Dragon's Blood Croton Summary Table 292
Summary of Reviewed Clinical Studies 293
Adverse Reactions or Side Effects 293
Details on Dragon's Blood Products and Clinical Studies 295
Echinacea 303
Preparations Used in Reviewed Clinical Studies 303
Echinacea Summary Table 304
Summary of Reviewed Clinical Studies 307
Reviews and Meta-Analyses of Clinical Studies 311
Adverse Reactions or Side Effects 312
Information from Pharmacopoeial Monographs 313
Details on Echinacea Products and Clinical Studies 321
Elderberry 351
Preparations Used in Reviewed Clinical Studies 351
Elderberry Summary Table 352
Summary of Reviewed Clinical Studies 353
Adverse Reactions or Side Effects 353
Information from Pharmacopoeial Monographs 353
Details on Elderberry Products and Clinical Studies 356
Evening Primrose 359
Preparations Used in Reviewed Clinical Studies 359
Evening Primrose Summary Table 360
Summary of Reviewed Clinical Studies 362
Systematic Reviews and Meta-Analyses 367
Adverse Reactions or Side Effects 368
Details on Evening Primrose Products and Clinical Studies 370
Garlic 403
Preparations Used in Reviewed Clinical Studies 403
Garlic Summary Table 404
Summary of Reviewed Clinical Studies 408
Meta-Analyses and Systematic Clinical Reviews 419
Epidemiological Studies 421
Adverse Reactions or Side Effects 421
Information from Pharmacopoeial Monographs 422
Details on Garlic Products and Clinical Studies 429
and this just goes on and on....
Great Book!
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