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Handbook of Comparative Genomics: Principles and Methodology
 
 
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Handbook of Comparative Genomics: Principles and Methodology [Hardcover]

Cecilia Saccone (Author), Graziano Pesole (Author)
5.0 out of 5 stars  See all reviews (3 customer reviews)

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Book Description

February 7, 2003 047139128X 978-0471391289 1
This comprehensive reference covers the comparative methodology involved in studying molecular evolution. Providing a practical introduction to the role of bioinformatics in comparative genomics, this publication further discusses the basic technology used in genome sequencing projects and provides an overview of genome storage databases currently in use.

This timely and cutting-edge text also:

  • Reviews the basic principles of genomics and gene expression analysis
  • Discusses analytic methods in proteomics and transcriptomics
  • Includes a comprehensive list of Web resource

Editorial Reviews

Review

...will provide interesting reading and perspective to almost everyone involved in biological sciences. -- Quarterly Review of Biology, March 2004

"…an excellent addition to the field of comparative genomics." (ASM News, December 2004)

“...will provide interesting reading and perspective to almost everyone involved in biological sciences.” (Quarterly Review of Biology, March 2004)

"...certainly deserves a place in institutional libraries...depth of material covered is right for the busy scientist...precise and detailed..." (Briefings in Functional Genomics & Proteomics, Vol 2(4), February 2004)

"...this book gives an illuminating look at the study of genomes through their sequence..." (Human Genomics, January 2004)

"...covers basic and applied problems in the emerging field of comparative functional genomics..." (Genetic Engineering News, Vol 23(14), 2003)

"...certainly deserves a place in institutional libraries...depth of material covered is right for the busy scientist...precise and detailed..." -- Briefings in Functional Genomics & Proteomics, Vol 2(4), February 2004

"...covers basic and applied problems in the emerging field of comparative functional genomics..." -- Genetic Engineering News, Vol 23(14), 2003

"...this book gives an illuminating look at the study of genomes through their sequence..." -- Human Genomics, January 2004

Review

"Handbook of Comparative Genomics is a pioneering composition illuminating the emerging scientific discipline of comparative evolutionary genomics. Professors Cecilia Saccone and Graziano Pesole have not only provided us with a treasure trove of molecular, structural and compositional information, but more importantly, they have produced a scholarly exegesis of empirical, statistical, bioinformatical, computational, and evolutionary methodology. The Handbook contains both introductory and advanced material, and manages to maintain a degree of lucidity that is as rare as it is indispensable in scientific discourse."
—Dan Graur, Ph.D., Gordon Professor of Life Sciences, Tel Aviv University

"...a unique and most welcome source of information and inspiration for anyone interested in genomics, from advanced undergraduates to experienced researchers."
—Wilfried W. de Jong, Ph.D., Department of Biochemistry, University of Nijmegen, The Netherlands


Product Details

  • Hardcover: 442 pages
  • Publisher: Wiley-Liss; 1 edition (February 7, 2003)
  • Language: English
  • ISBN-10: 047139128X
  • ISBN-13: 978-0471391289
  • Product Dimensions: 10.2 x 7.2 x 1 inches
  • Shipping Weight: 2.2 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (3 customer reviews)
  • Amazon Best Sellers Rank: #2,322,187 in Books (See Top 100 in Books)

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3 of 3 people found the following review helpful:
5.0 out of 5 stars Indispensable Book, March 5, 2003
By A Customer
This review is from: Handbook of Comparative Genomics: Principles and Methodology (Hardcover)
"Handbook of Comparative Genomics is a pioneering composition illuminating the emerging scientific discipline of comparative evolutionary genomics. Professors Cecilia Saccone and Graziano Pesole have not only provided us with a treasure trove of molecular, structural and compositional information, but more importantly, they have produced a scholarly exegesis of empirical, statistical, bioinformatical, computational, and evolutionary methodology. The Handbook contains both introductory and advanced material, and manages to maintain a degree of lucidity that is as rare as it is indispensable in scientific discourse." (Dan Graur, Ph.D., Gordon Professor of Life Sciences, Tel Aviv University)
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1 of 1 people found the following review helpful:
5.0 out of 5 stars "Welcome Source of Information", March 14, 2003
By A Customer
This review is from: Handbook of Comparative Genomics: Principles and Methodology (Hardcover)
"...a unique and most welcome source of information and inspiration for anyone interested in genomics, from advanced undergraduates to experienced researchers." --Wilfried W. de Jong, Ph.D., Department of Biochemistry, University of Nijmegen, The Netherlands
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5.0 out of 5 stars Interesting Reading, April 15, 2004
By A Customer
This review is from: Handbook of Comparative Genomics: Principles and Methodology (Hardcover)
"...will provide interesting reading and perspective to almost everyone involved in biological sciences." (Quarterly Review of Biology, March 2004)
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Inside This Book (learn more)
First Sentence:
While this book is being written, complete sequences of bacterial genomes are being produced at a rate of about two genomes per month, and the National Center for Biotechnology Information (NCBI) Web site (see the URL in Table 5.1) reports about 60 completely sequenced prokaryotic genomes. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
fungal mitochondrial genome project, isochore families, protein inventory, codon use, draft genome sequence, gene displacement, compositional asymmetry, comprehensive microbial resource, micros atellites, nonsynonymous sites, bait protein, plant mitochondrial genome, query sequence, mutational bias, electronic annotation, protein secondary structure prediction, topology prediction, complete mitochondrial genome, compositional bias, anchoring enzyme, relative rate test, gene density, segmental duplications, assembler version, paralogous genes
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Gene Ontology, Celera Genomics, European Bioinformatics Institute, Online Mendelian Inheritance, P-Num Plot, Saccharomyces Genome Database, Archaea Aeropyrum, Fungal Mitochondrial Genome Project, Gene Indices, International Protein Index, Mouse Genome Database, Rosetta Stone, Vector Alignment Search Tool
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