Handbook of Proteolytic Enzymes, with CD-ROM [Hardcover]

Alan J. Barrett (Editor), Neil D. Rawlings (Editor), J. Fred Woessner (Editor), Rawlings D Neil (Editor)

Book Description

Publication Date: October 27, 1998 | ISBN-10: 0120793709 | ISBN-13: 978-0120793709 | Edition: 1st

The Handbook of Proteolytic Enzymes is a complete, must-have reference work for biochemists, biotechnologists, and molecular biologists. This comprehensive work has 569 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses.

The Handbook is divided into five sections on peptidases of serine, cysteine, aspartic, metallo, and unknown catalytic mechanism. It is ordered according to a novel system of classification pioneered by the editors and used by IUBMB and SWISS-PROT.

Each chapter details a different enzyme, including:
* Name and history
* Activity and specificity
* Structural chemistry
* Preparation
* Biological aspects
* Distinguishing features
* References to further reading and databank sequence identifiers

The Handbook is accompanied by a CD-ROM that features specialized scissile bond, text and reference searches, zoomable 3D color enzyme structures, sequence alignments and extensive hyperlinks. It's an invaluable resource for researcher workers in biomedicine, biotechnology, biochemistry, molecular biology, chemistry, pharmacology, plant science, agriculture, and pharmaceutical companies.

Key Features
* The only complete reference on all proteolytic enzymes
* Comprehensive multi-authored work with over 560 chapters written by experts in the field
* Each chapter contains extensive cross-referencing and a comprehensive table of database sequence identifiers
* CD-ROM included featuring specialized scissile bond, text and reference searches, zoomable 3D color enzyme structures, sequence alignments and extensive hyperlinks

Editorial Reviews

Review

"The present Handbook of Proteolytic Enzymes by Barrett, Rawlings, and Woessner is an important and heroic accomplishment... for the first time in the history of enzymology it presents a rather complete hierarchical reference of the chemical and biological properties of proteases... I consider it an indispensable reference for the practicing enzymologists, protein chemists and molecular biologists generally. The authors, their contributors and the publisher have rendered a most valuable service to the students, scholars and general practitioners in making this compilation available at this time and deserve a round of applause for having done so with remarkable skill and devotion."
--Hans Neurath, Professor Emeritus of Biochemistry, University of Washington

"...highly recommended for anyone with an interest in proteolytic enzymes and is probably the only truly comprehensive handbook of this type available. It represents a massive effort by the editors and contributors and will likely be the primary source of such information in the future."
-Doody's Publishing Reviews

"...this classification scheme was the brain-child of Rawlings and Barrett (1993) and has gained wide acceptance as the major system to unify the previously rather arbitrary nomenclature of proteolytic enzymes...The Handbook of Proteolytic Enzymes is a much needed reference book in the field of peptidases. Not only does it provide a wealth of information for the vast majority of the individual enzymes discussed, but also it shows vividly the relationships among members of families and clans within the 4 major classes...It is a comprehensive treatise that will be extremely valuable not only to experts in the field but also to the general biochemical community."
-Michael N.G. James, MRC Canada, Group in Protein Structure and Function, Department of Biochemistry

"...a massive and definitive compilation of information on proteolytic enzymes and will no doubt be the standard work for years to come...the information collected here will be of great value to scientists working in practically the whole of biology as well as to the biotechnology industry...For the teacher, the book would be a valuable source of reference...and for generations of postgraduates and postdocs this will be a bible..."
-BIOCHEMICAL EDUCATION

Book Description

A two-volume set that covers exciting new developments on enzymes that are currently major targets of pharmaceutical research --This text refers to an alternate Hardcover edition.

See all Editorial Reviews

Product Details

• Hardcover: 1666 pages
• Publisher: Academic Press; 1st edition (October 27, 1998)
• Language: English
• ISBN-10: 0120793709
• ISBN-13: 978-0120793709
• Product Dimensions: 11.3 x 8.7 x 3.3 inches
• Shipping Weight: 7.5 pounds
• Amazon Best Sellers Rank: #5,375,032 in Books (See Top 100 in Books)