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Handbook of Statistical Genetics [Hardcover]

David J. Balding (Editor), Martin Bishop (Editor), Chris Cannings (Editor)
4.0 out of 5 stars  See all reviews (1 customer review)


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Handbook of Statistical Genetics (2 volume set) Handbook of Statistical Genetics (2 volume set)
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Book Description

March 14, 2001 0471860948 978-0471860945 1
A truly groundbreaking volume, the Handbook of Statistical Genetics is a timely, informative and highly accessible reference for both statisticians interested in genetical applications and geneticists seeking a deeper understanding of statistical methods in their field. It is divided into six main sections, encompassing the entire field of statistics in genetics:
? Bioinformatics
? Population Genetics
? Evolutionary Genetics
? Genetic Epidemiology
? Plant and Animal Genetics
? Applications
As the Human Genome Project (HGP) reaches its climax, with the complete sequence of mankind, science is fast approaching an exciting new stage in its ability to understand genetic forces in man.
In parallel to the HGP are major sequencing efforts in other organisms, enabling us to understand broader questions in evolution and classification. This explosion of data has led to an increased need for sophisticated statistical, mathematical and computational tools to enable complex data collection, analysis and interpretation of the results.
? Comprehensive coverage of the most pressing statistical issues in genetics.
? Offers a lucid introduction to newcomers, as well as providing invaluable information for more experienced researchers.
? Each chapter is written by a leading international authority from the field.
? Complemented by numerous examples, case studies, and references to useful resources on the web.
This authoritative reference will be ideal for both students and researchers working in genetics, including statisticians, geneticists, molecular biologists, biochemists and computer scientists.

Editorial Reviews

Review

"...aspires to contribute to developing methods for exploiting the new data explosion sparked by the Human Genome Project." (SciTech Book News, Vol. 25, No. 4, December 2001)

"This magnificent book attempts to catalogue and introduce all aspects of modern statistical genetics... I can thoroughly recommend it." (Short Book Reviews, Vol. 21, No. 3, December 2001)

"It is ideal for use as an introduction to a variety of statistical methods and provides an extensive source of references." (Human Genetics, 15 April 2002)

"...I highly recommend the volume for every library and those researchers interested in statistical methods...ideal for use as an introduction to a variety of statistical methods and provides an extensive source of references." (Human Genetics, Vol. 110, Published On-line: February 15, 2002)

"...the publisher has gathered...methodology very impressively in handbook format." (Technometrics, Vol. 45, No. 1, February 2003)

"...extremely well written and referenced work, which must come highly recommended..." (Statistical Methods in Medical Research, Vol.12, No.1, 2003)

"...an edited volume whose intellectual value may actually increase with time..."(Heredity, 2003)

"...individual chapters are of high quality...an excellent starting point...a must for all institutions dealing with the subject..." (Statistics in Medicine, Vol 23, 2004)

From the Back Cover

A truly groundbreaking volume, the Handbook of Statistical Genetics is a timely, informative and highly accessible reference for both statisticians interested in genetical applications, and geneticists seeking a deeper understanding of statistical methods in their field. It is divided into six main sections, encompassing the entire field of statistics in genetics.

As the Human Genome Project (HGP) reaches its climax, with the complete sequence of mankind, science is fast approaching an exciting new stage in its ability to understand genetic forces in man.

In parallel to the HGP are major sequencing efforts in other organisms, enabling us to understand broader questions in evolution and classification. This explosion of data has led to an increased need for sophisticated statistical, mathematical and computational tools to enable complex data collection, analysis and interpretation of the results.
* Comprehensive coverage of the most pressing statistical issues in genetics.
* Offers a lucid introduction to newcomers, as well as providing invaluable information for more experienced reasearchers.
* Each chapter is written by a leading international authority from the field.
* Complemented by numerous examples, case studies, and references to useful resources on the web.

Product Details

  • Hardcover: 890 pages
  • Publisher: John Wiley & Sons; 1 edition (March 14, 2001)
  • Language: English
  • ISBN-10: 0471860948
  • ISBN-13: 978-0471860945
  • Product Dimensions: 10 x 7.6 x 2.1 inches
  • Shipping Weight: 4 pounds
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #2,919,527 in Books (See Top 100 in Books)

 

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5 of 5 people found the following review helpful:
4.0 out of 5 stars Good overview of topics on quantitative aspects of genetics, May 9, 2001
By A Customer
This review is from: Handbook of Statistical Genetics (Hardcover)
The book is a collection of chapters written by experts in their respective fields. It contains both basic topics of genetics like chromosome maps and protein analysis as well as recent developments in evolutionary genetics like coalescence and phylogenetics. The topics on genetic epidemiology like linkage and association cover the main ideas, but the mathematical subtlities are not adequately explained in some of the cases. Since the target audience of this book are statistical geneticists, it would have been more beneficial if more quantitative insights were given. The chapters by Bruce Weir, Nicholas Schork and Ranajit Chakraborty provide some interesting practical applications of statistical genetics. With lots of controversies going around, it is apt to include the chapter on the ethical issues regarding the use of statistics in genetics.
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Inside This Book (learn more)
First Sentence:
Chromosome maps are a natural way of organizing genetic data about chromosomes. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
observed marker data, allelic peeling, species effective size, ancestral selection graph, octanucleotide preferences, genetic map functions, relative likelihood surface, real protein sequences, box weight matrix, internal exon prediction, local sequence similarity scores, modern human origins debate, peeling sequence, reconstructed ancestral sequences, uncorrected parsimony, local similarity scores, average effective population size, multiple linked markers, triplet composition, introgressed allele, sampled demes, expected coalescence time, different phylogenetic methods, genotype elimination, recombination graph
Key Phrases - Capitalized Phrases (CAPs): (learn more)
American Journal of Human Genetics, New York, National Academy of Sciences, Journal of Molecular Evolution, Theoretical Population Biology, Journal of Molecular Biology, Genetical Research, Nucleic Acids Research, Handbook of Statistical Genetics, John Wiley, Annals of Human Genetics, Livestock Production, Genetics Applied, Journal of Virology, Oxford University Press, Nature Genetics, Academic Press, Human Heredity, Journal of the Royal Statistical Society, Genome Research, Maynard Smith, Human Biology, Molecular Ecology, Old World, Systematic Zoology
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