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Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches
 
 

Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches [Hardcover]

Faramarz Naeim MD (Author), P. Nagesh Rao (Author), Wayne W. Grody (Author)
5.0 out of 5 stars  See all reviews (2 customer reviews)

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Book Description

0123706076 978-0123706072 December 3, 2008 1
This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review of immunophenotypic, cytogenetic and molecular findings. The text is balanced with large numbers of full color images, graphs, charts, and tables to assist the reader in understanding these highly technical issues.

* Emphasizes the immunophenotopic features, cytogenetic studies, and diagnostic molecular aspects of hematology
* Features a large number of images, charts and tables for the identification of hematologic disorders not only based on histopathologic features, but also with the use of advanced accessory techniques.

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Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches + Flow Cytometry in Neoplastic Hematology, Second Edition: Morphologic--Immunophenotypic Correlation + Flow Cytometry in Hematopathology: A Visual Approach to Data Analysis and Interpretation (Current Clinical Pathology)
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Editorial Reviews

Review

"This is a great book for practicing hematologists and medical oncologists as well as trainees and faculty in anatomic and clinical pathology. The writing is crisp, the figures and tables, all in color, are of high quality and informative and the book contains a wealth of information that is not readily available in reference textbooks of hematology, oncology or pathology. I give the book two thumbs up."

-- Robert I. Handin, MD, Senior Physician, Hematology Division, Brigham and Women's Hospital; Professor of Medicine, Harvard Medical School, Boston, MA, USA

"This book provides both the expert and the novice with the essential materials and didactic support needed to select, understand and interpret critically the vast number cell and tissue analyses now available from hematopathology laboratories. This text takes a commendably practical and clinically oriented approach to understanding the biologic basis of these tests, the technical, biological, and clinical pitfalls involved in their interpretation, and their power in aiding classification, prognostication and treatment selection. This is a very valuable teaching aid and reference volume for advanced students, residents in pathology, hematology oncology fellows, and specialists in blood disorders. The book should also be helpful to basic scientist working in these fields."

--Edward J. Benz, Jr., MD, President, Dana Farber Cancer Institute, Boston, MA, USA

"Hematopathology is a well written and comprehensive text that provides both strong background and specific details regarding hematological malignancies and their diagnosis. The text is easy to read and well organized. There are numerous high quality photomicrographs and comprehensive tables (particularly the cell differentiation molecules table) that complement the text. I particularly liked the background information regarding hematopoietic stem cells, and the practical aspects of the sections describing the principles of flow cytometry, and the techniques employed in karyotyping. This is something you don't often find in many texts."

-- Jeffery L. Kutok, MD, PhD, Associate Professor of Pathology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA

From the Back Cover

"This is a great book for practicing hematologists and medical oncologists as well as trainees and faculty in anatomic and clinical pathology. The writing is crisp, the figures and tables, all in color, are of high quality and informative and the book contains a wealth of information that is not readily available in reference textbooks of hematology, oncology or pathology. I give the book two thumbs up."

-- Robert I. Handin, MD, Senior Physician, Hematology Division, Brigham and Women's Hospital; Professor of Medicine, Harvard Medical School, Boston, MA, USA

"This book provides both the expert and the novice with the essential materials and didactic support needed to select, understand and interpret critically the vast number cell and tissue analyses now available from hematopathology laboratories. This text takes a commendably practical and clinically oriented approach to understanding the biologic basis of these tests, the technical, biological, and clinical pitfalls involved in their interpretation, and their power in aiding classification, prognostication and treatment selection. This is a very valuable teaching aid and reference volume for advanced students, residents in pathology, hematology oncology fellows, and specialists in blood disorders. The book should also be helpful to basic scientist working in these fields."

--Edward J. Benz, Jr., MD, President, Dana Farber Cancer Institute, Boston, MA, USA

"Hematopathology is a well written and comprehensive text that provides both strong background and specific details regarding hematological malignancies and their diagnosis. The text is easy to read and well organized. There are numerous high quality photomicrographs and comprehensive tables (particularly the cell differentiation molecules table) that complement the text. I particularly liked the background information regarding hematopoietic stem cells, and the practical aspects of the sections describing the principles of flow cytometry, and the techniques employed in karyotyping. This is something you don't often find in many texts."

-- Jeffery L. Kutok, MD, PhD, Associate Professor of Pathology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA

Key Features:

· Provides a multidisciplinary approach to the pathology of hematopoietic disorders by correlating morphology with biochemistry, immunophenotyping, cytogenetics, fluorescence in-situ hybridization, and molecular studies

· Covers both malignant and non-malignant hematologic disorders

· Each disease category covers etiology and pathogenesis, pathologic features, clinical aspects and differential diagnosis

· Over 540 figures of morphology, flow cytometry, immunohistochemistry, FISH analysis, karyotyping and molecular studies

· Over 115 tables to facilitate better understanding of the text material and act as summaries for quick reference


Product Details

  • Hardcover: 612 pages
  • Publisher: Academic Press; 1 edition (December 3, 2008)
  • Language: English
  • ISBN-10: 0123706076
  • ISBN-13: 978-0123706072
  • Product Dimensions: 10.8 x 8.7 x 1.3 inches
  • Shipping Weight: 4.4 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (2 customer reviews)
  • Amazon Best Sellers Rank: #1,097,978 in Books (See Top 100 in Books)

 

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1 of 1 people found the following review helpful:
5.0 out of 5 stars Multiparameter Diagnostic Approach, March 16, 2009
This review is from: Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches (Hardcover)
Modern diagnostic hematopathology relies on a combined approach using morphology, immunophenotyping (immunohistochemistry and flowcytometry) and molecular studies (cytogenetics, FISH and molecular genetics). Other standard textbooks in hematopathology primarily focused on morphology and immunophenotyping. Dr. Naeim's textbook marks an important shift in the approach to diagnostic hematopathology by combining all three modalities and discussing their strengths and weaknesses.

The first section of the book covers basic morphogenesis and principles of immunophenotyping and molecular studies. The next section covers myeloid and lymphoid neoplasms based on the new WHO classification. The last section focuses on benign hematology of the white cells, red cells and platelets. The highlight of the book is the profusion of high quality images (about 540), tables and illustrations. The authors are respected authorities in their areas. This book is as an excellent introduction to the integrated approach to diagnostic hematopathology for trainees, practicing pathologists, hematologists and oncologists.
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1 of 1 people found the following review helpful:
5.0 out of 5 stars Hematopathology, February 27, 2009
This review is from: Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches (Hardcover)
This is an excellent reference book which provides over 500 high quality photomicrographs along with well-written text. This book also includes most recent advances in the molecular pathology and provides a multidisciplinary approach for practicing pathologists and residents to understand both malignant and non-malignant hematologic disorders. I found this book is very useful for my daily practice and teaching, which assists me to address issues that I could not find appropriate answers from old books. I highly recommend this book to my colleagues and residents.
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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
clinical aspects, chronic myeloproliferative diseases, bone marrow pathology, reactive lymphadenopathies, international myeloma working group, erythroid preponderance, bone marrow biopsy section, cytotoxicity triggering receptor, myeloid left shift, marrow biopsy sections, biopsy section demonstrating, numerous blast cells, pure erythroid leukemia, bone marrow nucleated cells, dendritic cell sarcoma, bone marrow smear shows, leukemia demonstrating, monocytic nodules, bilineal acute leukemias, hepatosplenic lymphoma, stem cell subset, hematodermic neoplasms, circulating plasma cells, dendritic cell tumor, lymphoma demonstrating
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Leak Lymphoma, Cancer Genet Cytogenet, Clin Pathol, Mature B-Cell Neoplasms, Leak Res, Arch Pathol Lab Med, Sudan Black, Carr Opin, Pathology of Bone Marrow, Disorder of Red Blood Cells, Faramarz Naeim, Clin Invest, Genes Chromosomes Cancer, Blood Rev, Cancer Res, Mayo Clin Proc, Clin Cytom, Hematology Am Soc, Ann Intern Med, Principles of Immunophenotyping, United States, Leuk Lymphoma, Churchill Livingstone, Arch Intern Med, World Health Organization
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