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Heparin-Binding Proteins
 
 

Heparin-Binding Proteins [Hardcover]

H. Edward Conrad (Author)

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Book Description

0121860604 978-0121860608 October 3, 1997 1
This book describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways. The book also details the methodologies for studying these structures and their cellular metabolism. Heparin-Binding Proteins introduces the general nature of interactions between heparinoids and proteins, and presents the role for these structures in their interactions with the proteins of the hemostatic mechanisms, fibroblasts growth factors, superoxide dismutase, and lipoproteins.

Key Features
* Covers cellular metabolism of heparinoid proteoglycans
* Written by a distinguished expert in the field of carbohydrate biochemistry
* Describes the roles of heparan sulfate proteoglycans in
* * Blood coagulation and fibrinolysis
* Lipoprotein metabolism
* Superoxide dismutase activity
* Fibroblast growth factor responses of cells

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Editorial Reviews

Review

"...a remarkable achievement... I found reading this book to be highly rewarding... highly valuable as an introduction to various aspects of heparin/heparan sulfate chemistry and biology."
-Ulf Lindahl, Unviersity of Uppsala, Sweden, in JOURNAL OF MEDICINAL CHEMISTRY (1999)

From the Back Cover

Heparin-Binding Proteins is the comprehensive reference work on heparan sulfate proteoglycans, their structure, metabolism, and physiological roles. It describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways. The methodologies for studying these structures and their cellular metabolism are also detailed.
Key Features
* Covers cellular metabolism of heparinoid proteoglycans
* Written by a distinguished expert in the field of carbohydrate biochemistry
* Describes the roles of heparan sulfate proteoglycans in
* * Blood coagulation and fibrinolysis
* Lipoprotein metabolism
* Superoxide dismutase activity
* Fibroblast growth factor responses of cells

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Inside This Book (learn more)
First Sentence:
Heparin is a highly sulfated polysaccharide that is used clinically as an anticoagulant. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
endothelial cell heparan sulfate proteoglycan, active center loop, heparan sulfate metabolism, sulfated blocks, transmembrane core proteins, nitrous acid cleavage, antithrombin case, cell surface pool, culture medium pool, most heparan sulfates, heparan sulfate chains, cell surface heparan sulfate proteoglycan, heparan sulfate structures, unsulfated disaccharides, hydrazide formation, ovary cell mutant defective, smallest oligosaccharide, thrombin neutralization, core protein synthesis, heparan sulfate proteoglycan core protein, heparan sulfate synthesis, heparin biosynthesis, hexasaccharide sequence, hydrazinolysis reaction, total disaccharides
Key Phrases - Capitalized Phrases (CAPs): (learn more)
American Chemical Society, Cleaved Substrates, Determination of Heparinoid Structures, Prototypic Heparin-Binding Protein, Substrate Specificity of Heparin Lyase
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