Nagy Habib and a team of clinical laboratorians and physicians describe the wide variety of powerful new laboratory methods currently being used for investigating and treating hepatocellular carcinoma. The book focuses on gene therapy approaches, including the use of such vectors as lipids, such viruses as adenovirus and baculovirus, and virus detection assessment using electron microscopy. It provides preclinical and clinical data on the killing of cancer cells using tumor-suppressor genes, antisense compounds to growth factors, immunotherapy (remove gene), or virus-directed enzyme prodrug therapy. Hepatocellular Carcinoma: Methods and Protocols offers experimental and clinical researchers a rich source of both basic science and clinical information on today's optimal use of gene therapy to treat and manage patients suffering from hepatocellular carcinoma.
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Editorial Reviews
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"...The molecular techniques are presented in a very useful format...This is a unique book with tools presented that can be directly applied to bench, translational, and clinical research. The step-by-step protocols are comprehensive and easy to understand." -Doody's Health Science Book Review Journal
From the Back Cover
Advances in molecular characterization and novel gene-isolation techniques have vigorously expanded our understanding of hepatocellular carcinoma (HCC), a form of liver cancer that affects one million people annually, and generated many new therapeutic possibilities. In Hepatocellular Carcinoma: Methods and Protocols, Nagy Habib and a team of basic and clinical researchers describe the wide variety of powerful new laboratory-based molecular methods currently being used for investigating and treating this disease. The book focuses on gene therapy approaches, including the use of such vectors as lipids, adenovirus, and baculovirus, and virus detection assessment using electron microscopy. It also provides preclinical and clinical data on the killing of cancer cells using tumor-suppressor genes, antisense compounds to growth factors, immunotherapy (remove gene), and virus-directed enzyme prodrug therapy. A perspective on future treatment of the failing liver is given, along with a clinical protocol for p53 gene therapy. Hepatocellular Carcinoma: Methods and Protocols offers experimental and clinical investigators a rich source of both basic science and clinical information on today's optimal use of gene therapy to treat and manage patients suffering from hepatocellular carcinoma.
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0 of 2 people found the following review helpful:
3.0 out of 5 stars
penifit,
By eltayeb ahmed ali (africa) - See all my reviews
This review is from: Hepatocellular Carcinoma: Methods and Protocols (Methods in Molecular Medicine) (Hardcover)
agood book, i could learn alot of informations out of this book, thak you ...dear writer.
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Inside This Book
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First Sentence:
The incidence of HCC in Western countries is low, but it remains a serious health problem globally, causing an estimated 1,250,000 deaths every year worldwide (1). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
liver cell dysplasia, poststudy evaluations, liver dysplasia, tumor neovascularity, transcatheter arterial chemoembolization, separating gel solution, unresectable hepatocellular carcinoma, small hepatocellular carcinoma, wash vessel, antisense gene therapy, stacking gel solution, transfer stack, control clones, transcatheter arterial embolization, human hepatocellular carcinoma, tumor ablation, rinse cells, hepatic resection, cirrhotic patients, probe mixture, percutaneous ethanol injection, hepatic artery infusion, latex microspheres, hepatic decompensation, liver resection Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, Gene Ther, Humana Press Inc, Molecular Medicine, Cold Spring Harbor, New England Biolabs, New York, Bromphenol Blue, Introduction Hepatocellular, Becton Dickinson, Nucleic Acids Res, San Diego, The Netherlands, Cell Biol, Santa Cruz Biotechnology, Working Wash Buffer, Amersham Life Science, Magenta Microbiological Associates, Nature Genet, American Type Culture Collection, Boehringer Mannheim, Bond Elute, Cancer Chemother, Cancer Inst, Falcon Cell Culture Inserts New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The incidence of HCC in Western countries is low, but it remains a serious health problem globally, causing an estimated 1,250,000 deaths every year worldwide (1). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
liver cell dysplasia, poststudy evaluations, liver dysplasia, tumor neovascularity, transcatheter arterial chemoembolization, separating gel solution, unresectable hepatocellular carcinoma, small hepatocellular carcinoma, wash vessel, antisense gene therapy, stacking gel solution, transfer stack, control clones, transcatheter arterial embolization, human hepatocellular carcinoma, tumor ablation, rinse cells, hepatic resection, cirrhotic patients, probe mixture, percutaneous ethanol injection, hepatic artery infusion, latex microspheres, hepatic decompensation, liver resection Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, Gene Ther, Humana Press Inc, Molecular Medicine, Cold Spring Harbor, New England Biolabs, New York, Bromphenol Blue, Introduction Hepatocellular, Becton Dickinson, Nucleic Acids Res, San Diego, The Netherlands, Cell Biol, Santa Cruz Biotechnology, Working Wash Buffer, Amersham Life Science, Magenta Microbiological Associates, Nature Genet, American Type Culture Collection, Boehringer Mannheim, Bond Elute, Cancer Chemother, Cancer Inst, Falcon Cell Culture Inserts New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 31
books:
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24
books
cite this book:
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- Cancer: Principles and Practice of Oncology (Cancer: Principles & Practice (DeVita)(Single Vol.)) by Vincent T. DeVita Jr. MD on page 15, and page 165
- Primary Liver Cancer in Japan by Takayoshi Tobe on page 31, and page 32
- Diagnostic and Therapeutic Antibodies (Methods in Molecular Medicine) by Andrew J.T. George in Front Matter, and page 206
- Cancer: A Molecular Approach by Nicholas R. Lemoine on page 129
- Capillary Electrophoresis (Techniques in Analytical Chemistry) by Dale R. Baker in Front Matter
See all 31 books this book cites
- Drug Targeting: Strategies, Principles, and Applications (Methods in Molecular Medicine) by G. E. Francis in Front Matter
- Gene Therapy Protocols (Methods in Molecular Medicine) by Jeffrey R. Morgan in Front Matter
- Nonviral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) by Mark A. Findeis in Front Matter
- Hematologic Malignancies: Methods & Techniques (Methods in Molecular Medicine) by Guy B. Faguet in Front Matter
- Celiac Disease: Methods and Protocols (Methods in Molecular Medicine) by Michael N. Marsh in Front Matter
See all 24 books citing this book
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