The reader of this volume will be struck by three marked differences with Vol. 21 of the original HCN series. The first - awareness of the tremendous data-increment on adult-onset autosomal-dominant OPCA over the recent years led the editors to opt for a less-rigidly conceptualized and more realistic presentation of that topic, this presentation having two obvious merits: it stays close to clinical reality, and it leaves the field wide open for the ordering principle of molecular genetics to draw the definitive lines of the frame. The second conspicuous difference is the neuropathy-classification chapter based on the work of the WFN Research Group, and an exhaustive ataxia differential diagnosis chapter. The third and final difference to be noted on almost every page of this volume, is the revolutionary impact molecular genetics has exerted (and is continuing to exert) on aneurological, once rather academic and abstruse domain largely devoid oftherapeutic consequences. The very latest information on these developments is provided.
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As a reference...the work stands out; no other source can compare in terms of depth, diversity and organization -- Jnl. of the Neurological Sciences
As a reference...the work stands out; no other source can compare in terms of depth, diversity and organization -- Jnl. of the Neurological Sciences
As a reference...the work stands out; no other source can compare in terms of depth, diversity and organization -- Jnl. of the Neurological Sciences
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