"The author has certainly achieved his goal of providing an accessible introduction to human drug metabolism." (The Annals of Pharmacotherapy, June 2006)
" … for many who are just beginning to learn about drug metabolism because it deals with all of the relevant aspects." (Journal of Medicinal Chemistry, Vol. 49, No. 8, May 2006)
"Armed with the knowledge contained in this book, we should all be well on the way" (Pharmaceutical Physician, May 2006)
"…useful for many who are just beginning to learn about drug metabolism…a good addition to many personal and school libraries." (Journal of Medicinal Chemistry, April 20, 2006)
"...thumbs up for ambition." (Chemistry World, 1st March 2006)
"Overall this is an interesting book that provides a rather comprehensive overview of drug metabolism in humans" (Journal of Medicinal Chemistry, 2006 Volume 49. No 8)
From the Back Cover
After underlining the relationship between efficacy, toxicity and drug concentration, the book then considers how metabolising systems operate and how they impact upon drug concentration, both under drug pressure and during inhibition. Factors affecting drug metabolism, such as genetic polymorphisms, age and diet are discussed and how metabolism can lead to toxicity is explained. The book concludes with the role of drug metabolism in the commercial development of therapeutic agents as well as the pharmacology of some illicit drugs.
- focuses on a conceptual understanding of drug metabolism
- takes a user-friendly approach to the chemical aspect of drug metabolism
- includes a wealth of diagrams and illustrations
- provides strategies for maximising examination performance
Human Drug Metabolism: An Introduction will be an invaluable resource for students studying pharmacology, pharmacy, bio-molecular sciences, biochemistry, molecular biology, toxicology, dentistry and medicine in addition to healthcare professionals and postgraduates.