A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.
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"This is an excellent compendium about human stem cells..." -Biologist
From the Back Cover
Although there is great interest in the potential for using stem cells as cell replacements and other treatments for diseases that currently have no cure, research on the biology of human embryonic stem cells is still in its infancy. In Human Embryonic Stem Cells, pioneers, leaders, and experts in this emerging field join forces to address all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, these topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. The authors cover the criteria used by investigators in different fields to recognize mature phenotypes of specific tissues. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property. Reviewing the most pressing issues involved in human embryonic stem cell research, Human Embryonic Stem Cells, provides an invaluable sourcebook for researchers seeking a review of their basic biology and an unbiased assessment of their potential for new therapies.
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The announcement in February 1997 by researchers at the Roslin Institute in Edinburgh, Scotland of the successful cloning of a sheep named Dolly from adult mammary cells surprised the scientific community and captured the public's attention, provoking hopeful comments from political leaders, religious figures, and eminent scientists about potential benefits, as well as expressions of fears that it could lead to profound ethical transgressions. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
autologous cell therapies, associated steel factor, multipotent adult progenitor cells, embryonic ectoderm cells, primate embryonic stem cell line, human germ cell tumors, soluble steel factor, stem cell preparations, human embryonal carcinoma cell line, primate embryonic stem cells, human embryonal carcinoma cells, knockout serum replacement, allogeneic cell therapies, human neural stem cells, using human pluripotent stem cells, stem cell plasticity, somatic stem cells, pluripotent stem cell review group, pancreatic differentiation, neuronal progenitor cells, neuron grafts, pancreatic stem cells, human neurons derived, male genital ridge, human embryonic stem cell lines Key Phrases - Capitalized Phrases (CAPs): (learn more)
United States, Nature Biotechnol, Brain Res, Humana Press Inc, Nature Med, Cell Biol, National Institutes of Health, Cancer Res, Cell Res, Genes Dev, Nature Genet, European Patent Convention, Human Embryonic Stem Cells Edited, President Bush, President George, Cell Dev, New York, Accessed May, Bayh-Dole Act, Catholic Church, Layton Bioscience, Nuffield Council, President Clinton, United Kingdom, Cancer Inst New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The announcement in February 1997 by researchers at the Roslin Institute in Edinburgh, Scotland of the successful cloning of a sheep named Dolly from adult mammary cells surprised the scientific community and captured the public's attention, provoking hopeful comments from political leaders, religious figures, and eminent scientists about potential benefits, as well as expressions of fears that it could lead to profound ethical transgressions. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
autologous cell therapies, associated steel factor, multipotent adult progenitor cells, embryonic ectoderm cells, primate embryonic stem cell line, human germ cell tumors, soluble steel factor, stem cell preparations, human embryonal carcinoma cell line, primate embryonic stem cells, human embryonal carcinoma cells, knockout serum replacement, allogeneic cell therapies, human neural stem cells, using human pluripotent stem cells, stem cell plasticity, somatic stem cells, pluripotent stem cell review group, pancreatic differentiation, neuronal progenitor cells, neuron grafts, pancreatic stem cells, human neurons derived, male genital ridge, human embryonic stem cell lines Key Phrases - Capitalized Phrases (CAPs): (learn more)
United States, Nature Biotechnol, Brain Res, Humana Press Inc, Nature Med, Cell Biol, National Institutes of Health, Cancer Res, Cell Res, Genes Dev, Nature Genet, European Patent Convention, Human Embryonic Stem Cells Edited, President Bush, President George, Cell Dev, New York, Accessed May, Bayh-Dole Act, Catholic Church, Layton Bioscience, Nuffield Council, President Clinton, United Kingdom, Cancer Inst New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 15
books:
See all 15 books this book cites
3
books
cite this book:
- Spinal Cord Trauma: Regeneration, Neural Repair and Functional Recovery (Progress in Brain Research) by L. McKerracher on page 386
- Transgenic Animals by F. Grosveld in Back Matter
- Human Tumor Cells in Vitro by Jorgen Fogh on page 81
- Manipulating the mouse embryo: A laboratory manual by Brigid Hogan in Back Matter
- Understanding Farm Animals (Animals around us) by Ruth Thomson in Back Matter
See all 15 books this book cites
- Liberation Biology: The Scientific and Moral Case for the Biotech Revolution by Ronald Bailey in Back Matter (1), and Back Matter (2)
- Lab-on-Chips for Cellomics: Micro and Nanotechnologies for Life Science by Albert Berg on page 271
- Human Embryonic Stem Cells (Advanced Methods ( BIOS )) by Jon Odorico on page 298
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