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Human Gene Evolution (Human Molecular Genetics)
 
 
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Human Gene Evolution (Human Molecular Genetics) [Hardcover]

Stephen Cooper (Editor)
5.0 out of 5 stars  See all reviews (1 customer review)

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Book Description

0121878708 978-0121878702 November 17, 1999 1
Presents the principles of human gene evolution in a concise and easy to understand fashion. Uses examples of how evolutionary processes have molded present day genes, drawn from the evolution of humans and other primates, as well as from more primitive organisms. With increasing attention in this expanding area, this review forms a timely publication of our current knowledge of this important field.

Key Features
* Structure and function in the human genome
* The evolution of gene structure
* Mutational mechanisms in evolution

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Editorial Reviews

Review

"Professor Cooper has given us a comprehensive, authoritative, fascinating and masterful account of the evolutionary history of the human genes. Human Gene Evolution is recommended for the novice and the experienced alike."
--Professor Stylianos Antonarakis

From the Back Cover

The Human Genome Project is soon expected to yield the entire sequence of the human genome, providing an unparalleled opportunity to understand its structure, function and evolution. Human Gene Evolution bring together the highly dispersed literature on human gene structure, function, organization and expression, integrates this with our emerging knowledge of chromosome and genome structure, and discusses the nature of the mutational mechanisms that underlie evolutionary change.
A companion volume to the best-selling Human Gene Mutation by the same author, a central theme to this book is that mutations in human gene pathology and evolution represent two sides to the same coin, in that those same mutational mechanisms that have been frequently implicated in human pathology have also been involved in fashioning evolutionary change.
Human Gene Evolution is an authoritative and timely review of our current knowledge of this important field. It is essential reading for human molecular geneticists and for post-graduate students and interested clinicians.
"Professor Cooper has given us a comprehensive, authoritative, fascinating and masterful account of the evolutionary history of the human genes. Human Gene Evolution is recommended for the novice and the experienced alike." Professor Stylianos Antonarakis

Product Details

  • Hardcover: 500 pages
  • Publisher: Academic Press; 1 edition (November 17, 1999)
  • Language: English
  • ISBN-10: 0121878708
  • ISBN-13: 978-0121878702
  • Product Dimensions: 9.4 x 6.4 x 1.2 inches
  • Shipping Weight: 2.6 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #7,139,208 in Books (See Top 100 in Books)

 

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1 of 1 people found the following review helpful:
5.0 out of 5 stars an amazing compendium, March 22, 2003
By A Customer
This review is from: Human Gene Evolution (Human Molecular Genetics) (Hardcover)
This book is an amazing compendium of interesting facts about the evolution of our genome. It is comprehensive without being boring. I am writing this review in 2003, rather late for a 1999 book, because it is so good I felt it shouldn't be listed on Amazon without at least one review from a reader. I hope that the author will update it with a second edition incorporating new data from the sequencing of the human genome, which was "completed" after this book was published.
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Inside This Book (learn more)
First Sentence:
Nothing in biology makes sense except in the light of evolution. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
human gene evolution, haptoglobin gene cluster, extant thrombin, intron sliding, primordial exons, homologous unequal recombination, arm monomer, guinea pig gene, causing human genetic disease, copy number polymorphism, involucrin gene, orthologous positions, endogenous retroviral elements, olfactory receptor gene family, receptor gene cluster, human mucin genes, olfactory receptor genes, ancient conserved regions, ancestral protein, gene pathology, human pseudogenes, paralogous members, cognate transcription factors, human sex chromosomes, mammalian sex chromosomes
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, Old World, Nature Genet, Natl Acad, Trends Genet, Scientific Publishers, Cell Genet, Genome Res, New York, Complete Linked, Cell Biol, Human Genome Evolution, Nail Acad, Genes Devel, Cell Molec, Sinauer Associates, Alu Alu, Cold Spring Harb, Oxford University Press, Trends Biochem, Cancer Res, Immunology Today, Van Arsdell, Academic Press, Cum Opin
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