Human Molecular Genetics [Import] [Paperback]

Tom Strachan (Author), Andrew P. Read (Author)

Book Description

ISBN-10: 0471330612 | ISBN-13: 978-0471330615 | Publication Date: December 15, 1999 | Edition: 2nd

Human Molecular Genetics 2 Tom Strachan & Andrew P. Read "truly a Rolls Royce amongst textbooks" — Molecular Medicine Today "the best text to introduce students and scientists to the molecular aspects of human genetics" — Trends in Genetics "a beautifully crafted book" — Journal of Medical Genetics "addresses the gap between introductory textbooks and the primary literature. There’s no other textbook quite like it." — Nature Now extensively rewritten and updated, HMG2 guides students and researchers through the very latest developments in the most rapidly changing area of life science. The highly regarded structure of the bestselling first edition is retained, but a wealth of new data and features have been added to aid understanding of the principles of human molecular genetics:

• new material on cell types and the cell cycle, signal transduction, DNA mutation repair, and comparative genomics and evolution
• new material on recent advances in the study of gene expression and function, including the use of DNA microarrays
• the latest Genome Project data including an assessment of the impact of complete genome sequences and new approaches in functional genomics
• expanded coverage of common disease susceptibility
• new section on how best to obtain the latest data from web-based resources
• a range of new figures, with many more in full color
• the early use of hierarchical figures and flow charts to introduce principles described fully in later chapters
• new two-column layout to improve clarity further
• references systematically updated

HMG2 is the book of choice for readers requiring an authoritative and integrated approach to human genetics.

Editorial Reviews

Review

"Provides introductory material on DNA and chromosomes...describes principles and applications of cloning and molecular hybridization...presents a guide to...the human genome and human genes...examines mapping of the human genome, study of genetic diseases, and dissection and manipulation of genes."(SciTech Book News Vol. 25, No. 2 June 2001)

Product Details

• Paperback: 576 pages
• Publisher: Wiley-Liss; 2nd edition (December 15, 1999)
• Language: English
• ISBN-10: 0471330612
• ISBN-13: 978-0471330615
• Product Dimensions: 10.9 x 8.3 x 1.3 inches
• Shipping Weight: 3.4 pounds
• Average Customer Review: 4.8 out of 5 stars  See all reviews (5 customer reviews)
• Amazon Best Sellers Rank: #1,293,193 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

37 of 40 people found the following review helpful:

5.0 out of 5 stars The book to read for an in-depth background, May 15, 2001

By 

Dr. Lee D. Carlson (Baltimore, Maryland USA) - See all my reviews
(VINE VOICE)    (HALL OF FAME REVIEWER)    (REAL NAME)   

This review is from: Human Molecular Genetics (Paperback)

This book is a very complete overview of molecular biology as applied to human genetics. As someone interested in bioinformatics and computational biology, I read it to get a background in the biology/genetics behind these fields. That being said, I was glad I made the choice of this book as the authors do a fine job of explaining the relevant concepts and biological processes in genetics. In the light of the recent draft of the human genome, this edition of the book is especially timely. That being said, there is a lot of material covered, and to digest all of the terms and processes outlined takes a fair amount of time. The discussion on functional genomics and the post-genome sequencing era was particularly interesting. More could be said on gene sequencing validation as it applies to gene therapies and drug discovery. The most fascinating chapter was the one on genetic manipulation of animals as this is where genetic engineering has had its successful proving ground. Even though this is a science text, a discussion on the ethics of human genetic engineering would be appropriate, given some of the current attitudes about it. My opinion is that these technologies should move ahead with diligence; humankind cannot afford not to do so.

I would highly recommend this book to those who have the time to read through it, as it offers the necessary concepts needed to understand this fascinating area.

26 of 28 people found the following review helpful:

5.0 out of 5 stars Excellent for the working student!, February 2, 2000

By 

Vince (Montreal, Quebec, Canada McGill University) - See all my reviews

This review is from: Human Molecular Genetics (Paperback)

Being a graduate student in human genetics I was looking long and hard for a comprehensive text on how and why experiment are done in the lab, and the scientific basis for these experiments. This book is the closest one I have seen that accomplishes all these goals. It is a little light on the theoretical side of genetics (e.g. Mendelian etc); however, there are many other texts out there that can substitute for this flaw, but only a few that do what this one does. I recommend this book for students who are familiar with genetics but need to understand the practical side to it.

5 of 8 people found the following review helpful:

5.0 out of 5 stars An excellent text! For undergrad and grad students., May 6, 2000

By 

Math PC (Pasadena, CA, USA) - See all my reviews

This review is from: Human Molecular Genetics (Paperback)

Very comprehensive reading. It sure gives the reader a thorough explanation of the concept. Each chapter provides clear, yet detailed illustrations. Further explanations are given on several key concepts by including "highlights" for a particular topic. Although this book tackles more general knowledge on human genetics, it sure is highly recommended to students or professionals starting to learn Human Genetics.