Huntington's Disease (Oxford Monographs on Medical Genetics, 45) [Hardcover]

Gillian Bates (Editor), Peter Harper (Editor), Lesley Jones (Editor)

Book Description

Publication Date: November 14, 2002 | ISBN-10: 0198510608 | ISBN-13: 978-0198510604 | Edition: 3

It is now almost a decade since the identification of the Huntington's Disease gene and its mutation. Major advances in our understanding of the disorder have been made during this time. Since publication of the first two editions, much more extensive evidence exists on how the HD mutation actually causes brain pathology. Experimental tools are now available to take this research further towards new therapeutic approaches.
Due to these major changes, this well-established book has been radically updated. An international group of leaders in their particular fields cover the major recent advances in the genetics and neurobiology of the disease. Developments in our understanding of how the molecular basis of the disorder results in brain degeneration, with full coverage of transgenic animal models, neurochemical studies and advances in neuropathology are discussed in detail. The clinical sections cover both neurological and psychiatric aspects as well as new developments in therapy.
This book will continue to provide an invaluable source of information for clinicians and scientists involved with Huntington's Disease, including geneticists, psychiatrists and neurologists and basic research workers in genetics and neurobiology.

Editorial Reviews

Review

"The editors - Gillian Bates, Peter Harper, and Lesley Jones - have for some time been in the first rank of HD research. Their own insights and knowledge, together with those of other contributors, have admirably updated and expanded the already impressive first and second editions (edited by Peter Harper) to present a comprehensive view of the current understanding of HD." -Human Genetics

About the Author

Professor Gill Bates, Medical and Molecular Genetics, GKT School of Medicine King's College, Guy's Hospital, London, UK Professor Peter Harper, Institute of Medical Genetics, University Hospital of Wales Heath Park, Cardiff, Wales, UK Dr Lesley Jones, Institute of Medical Genetics, University Hospital of Wales, Heath Park, Cardiff, Wales, UK

Product Details

• Hardcover: 574 pages
• Publisher: Oxford University Press, USA; 3 edition (November 14, 2002)
• Language: English
• ISBN-10: 0198510608
• ISBN-13: 978-0198510604
• Product Dimensions: 9.4 x 6.7 x 1.4 inches
• Shipping Weight: 2.6 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #2,929,031 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

1 of 1 people found the following review helpful:

5.0 out of 5 stars Very informative book, December 22, 2004

By 

Marsha Miller (Wilmington, DE United States) - See all my reviews
(REAL NAME)   

This review is from: Huntington's Disease (Oxford Monographs on Medical Genetics, 45) (Hardcover)

This is an excellent, comprehensive book about Huntington's Disease. It is written for doctors, scientists, and other professionals dealing with Huntington's Disease but can also be read by Huntington's Disease families who wish to gain a deeper understanding of the disease. Each chapter is written by experts. There is information about the history of Huntington's Disease, its neuropathology, the psychiatric and behavioral problems, research, genetics, epidemiology, and the treatment of symptoms.

In addition the information about HD that has been published in medical and scientific journals, there is some valuable information from clinical practice that can't be found elsewhere.

I purchased the book to help me answer questions posed by readers of my HD websites and I have found it to be very valuable.