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Male Hypogonadism (Contemporary Endocrinology)
 
 
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Male Hypogonadism (Contemporary Endocrinology) [Hardcover]

Stephen J. Winters (Editor)

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Book Description

1588291316 978-1588291318 December 12, 2003 1
This lucid interpretation of the latest scientific information on male reproductive endocrinology provides a thorough understanding of the pathophysiology, clinical characteristics, and treatments for disorders that adversely affect testicular function. The authors focus on the specific causes of gonadotropin deficiency and testicular failure arising from disorders of the brain and the testis and from gene defects and chronic illness. Additional chapters describe the endocrine mechanism for the decline of testicular function with aging, summarize the data supporting the negative impact of environmental toxins on testicular function, and discuss the testicular consequences of exercise and obesity.

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Editorial Reviews

From The New England Journal of Medicine

Male reproductive health has become an important focus of health services in many countries. Poor semen quality is a widespread problem, and both young and elderly men often seek medical advice regarding symptoms of hypogonadism, including sexual dysfunction. However, andrology -- the clinical area of expertise that covers these medical problems -- has not yet been given sufficient attention in the health care systems of most countries. Therefore, training of doctors in this medical discipline is often superficial and lacking in uniformity. This excellent book, edited by leading American andrologist Stephen J. Winters, covers most problems in this field. It is unavoidable that a book containing 19 chapters written by 37 contributors turned out somewhat uneven with regard to style and quality. However, the list of authors is impressive. They represent some of the best American, European, and Australian research groups in andrology. A clear benefit is the inclusion of information on topics that may be difficult to find in other books, such as the congenital cause of adult symptoms of hypogonadism and hypogonadism in congenital adrenal hyperplasia. The latter chapter should prove useful not only for endocrinologists treating patients with hypogonadism but also for urologists, since the "adrenal nests" in men with congenital adrenal hyperplasia can mimic malignant germ-cell tumors. The chapters on the effects of irradiation and chemotherapy are also important additions to the available literature. I also want to highlight the chapters on androgens, sex hormone-binding globulin, and androgen-replacement therapy. The editor himself is an internist, and perhaps his selection of information on the pediatric aspects of hypogonadism is less than comprehensive. A pediatric endocrinologist may miss information on the possibility of treatment of boys with hypogonadism with oral androgens and on the long-term outcome of the treatment of micropenis and male pseudohermaphroditism. Despite these minor criticisms, I recommend this book as a timely update for all endocrinologists and urologists who care for patients with hypogonadism, male infertility, or both. It will also be useful as an introduction to these medical specialties for doctors during their training years. Niels E. Skakkebaek, M.D.
Copyright © 2005 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.

Review

"...an excellent guide for clinicians and researchers, as well as students of andrology interested in understanding the causes and possible therapies for male hypogonadism... a valuable addition to the bookshelf of any clinician or researcher interested in this field." -Trends in Endocrinology and Metabolism

"...this is a great book...concise, well-written, informative, and current." - American College of Physicians

"Well illustraed, tabulated and referenced. Of great interest to pediatric endocrinologists and andrologists." - Pediatric Endocrinology Reviews

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Inside This Book (learn more)
First Sentence:
The proximate regulator of testicular function is gonadotropin-releasing hormone (GnRH), which is produced in neurons scattered throughout the anterior hypothalamus. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
attempted paternity, spermatogenesis stimulation, partial gonadotropin deficiency, germ cell counts, normal sperm density, testicular adrenal rest tissue, spermatogenesis recovery, normal adult male range, adrenal rest tumors, androgen deficiency symptoms, congenital hypogonadotropic hypogonadism, stem cell renewal, testicular location, nadal men, testicular dysgenesis syndrome, low testosterone concentrations, fertile eunuch syndrome, reserve stem cells, bioavailable testosterone levels, unilateral group, unilateral orchidectomy, germ cell numbers, unilateral cryptorchidism, differentiated spermatogonia, renewing stem cells
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Clin Endocrinol Metab, Fertil Steril, Hum Reprod, Biol Reprod, New York, Endocr Rev, Sports Med, Steroid Biochem, Pediatr Surg, Horm Res, Clin Invest, Humana Press Inc, Therapeutic Principles Edited, Acta Endocrinol, Proc Natl Acad Sci, Appl Physiol, Biol Chem, Mol Endocrinol, Nat Genet, Mol Cell Endocrinol, Young Older, Aging-Related Hypoandrogenemia, Clin Oncol, Med Genet, Reprod Fertil
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