This book is based on the FEMS/SGM-sponsored laboratory course `Immunochemical and Molecular Genetic Analysis of Bacterial Pathogens and their Virulence Determinants'. The volume deals, in review form, with the contribution made to virulence by individual surface structures and toxins. Later chapters detail methodology related to the cloning of virulence genes and to the purification, assay and immuno/biochemical analysis of their products. In producing this volume recognition has been made of the fact that research scientists need, as two of their basic requirements, a series of tested protocols which may be readily applied to the problem at hand, and topical reviews which succinctly summarize progress in the field. Immunochemical and Molecular Genetic Analysis of Bacterial Pathogens is a companion to the 1985 Elsevier Publication `Enterobacterial Surface Antigens: Methods for Molecular Characterization' (Korhonen, T.K., Dawes, E.A., and Makela, P.H., eds.) also based on a related FEMS laboratory course.
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