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Immunology: Understanding The Immune System [Hardcover]

Klaus D. Elgert
3.5 out of 5 stars  See all reviews (4 customer reviews)

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Book Description

September 8, 2009 0470081570 978-0470081570 2
  • Blends biology, clinical science, genetics, and molecular biology of the immune system to provide a complete account of our knowledge of immunology
  • New features include full-color artwork and design, over 50 new figures, and text that has been completely revised to reflect the very latest references
  • Incorporates a variety of pedagogical aids to assist students in the learning process, including chapter outlines, objectives, and summaries, as well as a self-evaluation section

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Immunology: Understanding The Immune System + Schaechter's Mechanisms of Microbial Disease
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Editorial Reviews

From the Publisher

A comprehensive and extremely accessible textbook written by a professor with over 20 years of experience teaching immunology courses. Elgert carefully melds together biology, clinical science, genetics and molecular biology of the immune system to provide a coherent and complete account of our knowledge of immunology. A variety of pedagogical aids, including chapter outlines, objectives and summaries as well as a self-evaluation section, assist students in the learning process. --This text refers to an out of print or unavailable edition of this title.

From the Back Cover

Immunology: Understanding the Immune System, Second Edition has been thoughtfully and meticulously updated to incorporate the many developments that have occurred in the field since publication of the previous edition. In addition to the consolidation, reconstruction, and revision of key material, features completely new to this edition include: three new chapters on innate immunity, immunodeficiencies, and immunity to microbes; more than fifty new figures; coverage of the latest knowledge on signaling pathways, lymphocyte trafficking, mucosal immunity, molecular mechanisms of receptor diversity, the T-lymphocyte immunological synapse, B-lymphocyte subsets, dendritic cell-driving of CD-4+ T-cell subset activities, biology of the CD-4+ T-cell TH17 subset and regulatory T-cell, cross-presentation, mechanisms of tolerance induction, immunoediting and tumor camouflage and the connection between inflammation and cancer development, immunogenetics of primary immunodeficiencies and the immunology of HIV infections and AIDS, and vaccines; and more—all immersed in full-color artwork, design, and user-friendly text.

This Second Edition provides a completely up-to-date introduction to immunology through its careful investigation of:

  • Cells and organs of the human system

  • Innate immunity

  • Antigens and antibodies

  • Antigen-antibody interactions and some experimental systems

  • Genetics of antibody formation and structure

  • The major histocompatibility complex and development of immunity

  • T-cell receptor complex

  • Cytokines

  • Cellular interactions

  • Hypersensitivities

  • Immunologic tolerance and autoimmunity

  • Transplantation immunology

  • Tumor immunology

  • Immunodeficiencies

  • Immunity to microbes

Successfully blending biology, clinical science, genetics, and molecular biology, this book represents a complete account of our knowledge of immunology. It is complemented with a number of pedagogical aids that assist readers in the learning process, including chapter outlines, objectives, mini-summaries that provide "mental breathers" within the chapter to reassess the material just covered, full-chapter summaries, figures, and a self-evaluation section. The book ends with anextensive glossary and an appendix. It serves as an excellent textbook for courses in the life and medical sciences at the upper-undergraduate and graduate levels and as a reference for practicing scientists and clinical researchers.


Product Details

  • Hardcover: 726 pages
  • Publisher: Wiley-Blackwell; 2 edition (September 8, 2009)
  • Language: English
  • ISBN-10: 0470081570
  • ISBN-13: 978-0470081570
  • Product Dimensions: 11 x 8.7 x 1.6 inches
  • Shipping Weight: 4.3 pounds (View shipping rates and policies)
  • Average Customer Review: 3.5 out of 5 stars  See all reviews (4 customer reviews)
  • Amazon Best Sellers Rank: #1,488,790 in Books (See Top 100 in Books)

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Customer Reviews

3.5 out of 5 stars
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Most Helpful Customer Reviews
4 of 4 people found the following review helpful
2.0 out of 5 stars Klaus must update or perish March 12, 2006
Format:Hardcover
Just a quick note: Dr. Elgert's text is 10 years old.. 10! That's before the human genome came out, and what's more, the book is hopelessly outdated on a number of points. First of all, a lot of good science has been put out in the 10 years since its publication. Second, his illustrations look like their were made in MSPaint (and they very well may have been). Moreover, he reprinted his old edition at some point, but in black and white, and on rough, heavier paper. Buyer beware - the cover is identical.

LUCKILY.. if you don't go to Virginia Tech, I'm sure you're not in danger of exposure to this opaque anachronism of a textbook...
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2 of 3 people found the following review helpful
4.0 out of 5 stars Clear and Easy to read March 30, 2000
By A Customer
Format:Hardcover
It's very good textbook, easy to read and understand. I'm waiting for the new and up-to-date edition from the author, if possible.
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Format:Hardcover
When we survey libraries, including med school, university and private research labs, Elgert, though dated, is cited consistently in the top 10 in Immunology.

Yet, when we poll professors, med students and practicing teachers (both practicing immunology and teaching), for over a decade, a little 141 page, 8.5 x 11" monograph comes out in the top three! The book is Dr. Sompayrac's: How the Immune System Works, Includes Desktop Edition.

I'm adding this supplement to the reviews on this text to help any student struggling with macro concepts, and any professor who wants their class to really GET immunology. Here is my review from that book's Amazon page in case you want to consider this (I have nothing to do with the authors or publishers of this text, this is only for YOUR benefit, our readers and shoppers):

A few reviews have said that this little 141 page text is "dated." Two persepectives:

1. The material covered is timeless. Our understanding of T and B cells will evolve over time, but the basic function, and the ideas of receptor sites, etc. are so fundamental that a few decades here or there cannot possibly subtract from the immense value of this text.

2. Current thinking ("2020") is that we're entering an era of completely recasting the immune system, with as revolutionary a paradigm shift as recombinant DNA itself. One aspect of this is thinking of this system as multiple systems (6 or more in some literature). Another is the role of microRNA (small ds- double stranded RNA) and the epigenomic phenomena of RNA-interference.

These phenomena don't subtract from antibody or cell mediated immunity as models, they ADD to them.
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1 of 2 people found the following review helpful
3.0 out of 5 stars BUYER BEWARE!! May 10, 2010
Format:Hardcover|Verified Purchase
I purchased this book a few months ago for the course I am taking. The book is well written and provides a wealth of information.
HOWEVER, BEWARE!! This book does NOT come with ANY type of internet or computer support of ANY kind!!! There is no CD with the book, no supporting website, etc. So if you have even the simplest of questions that you would rather not bother your professor with (or have at 2 am when you seem to be alone), there is nothing to help you with this.
Like I said, the book is wonderful but the Author and/or publishing company needs to get with the 21st Century as well as with "Today's Student".
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